2. Gene
  3. Chd5 - chromodomain helicase DNA binding protein 5 Gene

Chd5 - chromodomain helicase DNA binding protein 5 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: CHD-5; 4930532L22Rik; B230399N07Rik

基因 ID: 269610 | 基因类型: protein coding

关于 Chd5

功能概要

Enables H3K27me3 modified histone binding activity and histone deacetylase binding activity. Involved in several processes, including cerebral cortex neuron differentiation; positive regulation of signal transduction by p53 class mediator; and spermatogenesis, exchange of chromosomal proteins. Located in heterochromatin and nucleus. Part of NuRD complex. Is expressed in central nervous system and dorsal root ganglion. Orthologous to human CHD5 (chromodomain helicase DNA binding protein 5). [provided by Alliance of Genome Resources, Apr 2022]

Chd5 基因产物(3)

mRNA Protein Name
NM_001081376.1 NP_001074845.1 chromodomain-helicase-DNA-binding protein 5 isoform 1
NM_001369243.1 NP_001356172.1 chromodomain-helicase-DNA-binding protein 5 isoform 3
NM_029216.2 NP_083492.2 chromodomain-helicase-DNA-binding protein 5 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables H3K27me3 modified histone binding IDA
IDA: 通过直接分析推断
23948251 MGI
enables histone binding IDA
IDA: 通过直接分析推断
23318260 MGI
enables histone deacetylase binding IPI
IPI: 通过物理相互作用推断
21931736 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
21931736 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cerebral cortex neuron differentiation IMP
IMP: 通过突变表型推断
23948251 MGI
involved in negative regulation of cell population proliferation IMP
IMP: 通过突变表型推断
17289567 MGI
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
23318260 MGI
involved in positive regulation of signal transduction by p53 class mediator IMP
IMP: 通过突变表型推断
17289567 MGI
involved in regulation of cell differentiation IMP
IMP: 通过突变表型推断
23318260 MGI
involved in sperm DNA condensation IMP
IMP: 通过突变表型推断
24252660 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of NuRD complex IDA
IDA: 通过直接分析推断
21931736 MGI
located in heterochromatin IDA
IDA: 通过直接分析推断
23318260 MGI
located in nucleus IDA
IDA: 通过直接分析推断
23948251 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

chromodomain-helicase-DNA-binding protein 5

ATP-dependent helicase CHD5

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-118780 CHD-5 Antagonist 98.0% 否
HY-RS05373 GET1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS02610 CHD5 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS02611 CHD6 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS07062 KALRN Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18344 Chd5 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24823 Chd5 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Chd5 NCBI NCBI:26038
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