2. Gene
  3. Abca3 - ATP-binding cassette, sub-family A (ABC1), member 3 Gene

Abca3 - ATP-binding cassette, sub-family A (ABC1), member 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Abc3; ABC-C; 1810036E22Rik

基因 ID: 27410 | 基因类型: protein coding

关于 Abca3

功能概要

Predicted to enable ABC-type xenobiotic transporter activity; phosphatidylcholine flippase activity; and phosphatidylcholine transfer activity. Involved in several processes, including glycerophospholipid metabolic process; phospholipid homeostasis; and surfactant homeostasis. Located in alveolar lamellar body membrane. Is expressed in several structures, including cardiovascular system; genitourinary system; gut; nervous system; and respiratory system. Used to study pulmonary alveolar proteinosis. Human ortholog(s) of this gene implicated in pulmonary alveolar proteinosis. Orthologous to human ABCA3 (ATP binding cassette subfamily A member 3). [provided by Alliance of Genome Resources, Apr 2022]

Abca3 基因产物(2)

mRNA Protein Name
NM_001039581.2 NP_001034670.1 phospholipid-transporting ATPase ABCA3
NM_013855.3 NP_038883.2 phospholipid-transporting ATPase ABCA3
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in lung development IMP
IMP: 通过突变表型推断
17540762 MGI
involved in organelle assembly IMP
IMP: 通过突变表型推断
17540762 MGI
involved in phosphatidylcholine metabolic process IMP
IMP: 通过突变表型推断
17267394 MGI
involved in phosphatidylglycerol metabolic process IMP
IMP: 通过突变表型推断
17142808 MGI
involved in phospholipid homeostasis IMP
IMP: 通过突变表型推断
20190032 MGI
involved in regulation of lipid biosynthetic process IMP
IMP: 通过突变表型推断
20190032 MGI
involved in regulation of lipid transport IMP
IMP: 通过突变表型推断
20190032 MGI
involved in surfactant homeostasis IMP
IMP: 通过突变表型推断
17142808 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in alveolar lamellar body membrane IDA
IDA: 通过直接分析推断
11940594 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

phospholipid-transporting ATPase ABCA3

ATP-binding cassette sub-family A member 3

xenobiotic-transporting ATPase ABCA3

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00041 ABCA3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20843 Abca3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27357 Abca3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Abca3 NCBI NCBI:21
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