2. Gene
  3. Gm2a - ganglioside GM2 activator Gene

Gm2a - ganglioside GM2 activator Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 282838 | 基因类型: protein coding

关于 Gm2a

功能概要

Enables lipid transporter activity and Phospholipase activator activity. Contributes to beta-N-acetylgalactosaminidase activity. Involved in ganglioside metabolic process; lipid transport; and positive regulation of hydrolase activity. Located in several cellular components, including apical plasma membrane; basolateral plasma membrane; and cytoplasmic side of plasma membrane. Human ortholog(s) of this gene implicated in GM2 gangliosidosis and GM2 gangliosidosis, AB variant. Orthologous to human GM2A (GM2 ganglioside activator). [provided by Alliance of Genome Resources, Apr 2022]

Gm2a 基因产物(1)

mRNA Protein Name
NM_172335.2 NP_758838.2 ganglioside GM2 activator precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
contributes to beta-N-acetylgalactosaminidase activity IDA
IDA: 通过直接分析推断
9770472 RGD
enables lipid transporter activity IDA
IDA: 通过直接分析推断
8948454 RGD
enables phospholipase activator activity IDA
IDA: 通过直接分析推断
9770472 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in ganglioside metabolic process IDA
IDA: 通过直接分析推断
9770472 RGD
involved in lipid transport IDA
IDA: 通过直接分析推断
8948454 RGD
NOT involved in membrane fusion IDA
IDA: 通过直接分析推断
8948454 RGD
involved in positive regulation of hydrolase activity IDA
IDA: 通过直接分析推断
9770472 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
10073593 RGD
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
10073593 RGD
located in cytoplasmic side of plasma membrane IDA
IDA: 通过直接分析推断
10073593 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ganglioside GM2 activator

GM2 ganglioside activator protein

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS29483 GM2A Cattle Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS05513 GM2A Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18134 Gm2a Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24609 Gm2a Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gm2a NCBI NCBI:2760
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