2. Gene
  3. GPR31 - G protein-coupled receptor 31 Gene

GPR31 - G protein-coupled receptor 31 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：G 蛋白偶联受体 31

种属: Homo sapiens

同用名: HETER; HETER1; 12-HETER

基因 ID: 2853 | 基因类型: protein coding

关于 GPR31

Cytogenetic location: 6q27 Genomic coordinates (GRCh38): 6:167,155,247-167,157,980 (from NCBI)

This gene has 1 transcript (splice variant), 201 orthologues and 15 paralogues.

功能概要

启用 G 蛋白偶联受体活性和花生四烯酸结合活性。参与 G 蛋白偶联受体信号通路和对酸性 pH 值的反应。位于质膜。 [由基因组资源联盟提供，2022 年 4 月]

Enables G protein-coupled receptor activity and arachidonic acid binding activity. Involved in G protein-coupled receptor signaling pathway and response to acidic pH. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

GPR31 基因产物(1)

mRNA Protein Name
NM_005299.3 NP_005290.2 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G protein-coupled receptor activity IDA
IDA: 通过直接分析推断
21712392 GOA
enables arachidonate binding IDA
IDA: 通过直接分析推断
21712392 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
28619714 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
21712392 GOA
involved in response to acidic pH IDA
IDA: 通过直接分析推断
31119277 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane IDA
IDA: 通过直接分析推断
21712392 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

GPR31 蛋白结构

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (31 - 282)

  • 0
  • 100
  • 200
  • 300
  • 319 a.a.
蛋白主名 其他名称

12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor

12-(S)-HETE acid receptor

关联疾病

疾病名称 别名
Ischemia

Acute Coronary Syndrome
Vulvar Dystrophy

Dystrophy Of Vulva
Prostate Cancer

Prostate Carcinoma

Prostate Cancer, Familial

Prostate Neoplasm

Prostate Cancer, Somatic

Prostate Cancer, Susceptibility To

Prostatic Cancer

Prostatic Neoplasms

Hereditary Prostate Cancer

Prostatic Neoplasm

Cancer Of Prostate

Carcinoma Of Prostate

Familial Prostate Cancer

Familial Prostate Carcinoma

Malignant Tumor Of Prostate

Malignant Neoplasm Of Prostate

Prostate Cancer, Familial, Susceptibility To

Malignant Tumor Of The Prostate

Ngp - New Growth Of Prostate

Tumor Of The Prostate

Prostate Cancer, Hereditary

Cancer Of The Prostate

Malignant Neoplasm Of The Prostate

Prostatic Carcinoma

PC

Prca

Cancer, Prostate

Malignant Prostatic Tumour

Malignant Tumour Of Prostate

Primary Prostate Cancer

Primary Malignant Neoplasm Of Prostate

Prostate Gland Cancer
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS20941 Gpr31 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS05701 GPR31 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27458 Gpr31 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris GPR31 VGNC VGNC:41430
Macaca mulatta GPR31 VGNC VGNC:104403
Mus musculus GPR31 MGD MGI:1354372
Rattus norvegicus GPR31 RGD RGD:1305187
Bos taurus GPR31 VGNC VGNC:29582
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