1. Gene
  2. Uts2 - urotensin 2 Gene

Uts2 - urotensin 2 Gene

种属: Rattus norvegicus

同用名: Ucn2

基因 ID: 29180 | 基因类型: protein coding

关于 Uts2

功能概要

Predicted to enable hormone activity. Involved in several processes, including negative regulation of secretion; regulation of blood pressure; and regulation of heart rate. Located in extracellular space. Used to study hypertension. Biomarker of asthma; cardiomyopathy; endomyocardial fibrosis; myocardial infarction; and pulmonary hypertension. Human ortholog(s) of this gene implicated in gestational diabetes and type 2 diabetes mellitus. Orthologous to human UTS2 (urotensin 2). [provided by Alliance of Genome Resources, Apr 2022]

Uts2 基因产物(1)

mRNA Protein Name
NM_019160.2 NP_062033.1 urotensin-2 precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in blood vessel diameter maintenance IDA
IDA: 通过直接分析推断
17097764 RGD
involved in negative regulation of blood pressure IDA
IDA: 通过直接分析推断
12217424 RGD
involved in negative regulation of glomerular filtration IDA
IDA: 通过直接分析推断
16531985 RGD
involved in negative regulation of heart rate IDA
IDA: 通过直接分析推断
12217424 RGD
involved in negative regulation of insulin secretion IMP
IMP: 通过突变表型推断
17931748 RGD
involved in negative regulation of urine volume IDA
IDA: 通过直接分析推断
16531985 RGD
involved in positive regulation of angiogenesis IDA
IDA: 通过直接分析推断
17089015 RGD
involved in positive regulation of blood pressure IDA
IDA: 通过直接分析推断
12217424 RGD
involved in positive regulation of cell differentiation IDA
IDA: 通过直接分析推断
18475149 RGD
involved in positive regulation of circadian sleep/wake cycle, REM sleep IDA
IDA: 通过直接分析推断
15944374 RGD
involved in positive regulation of circadian sleep/wake cycle, wakefulness IDA
IDA: 通过直接分析推断
15944374 RGD
involved in positive regulation of collagen biosynthetic process IDA
IDA: 通过直接分析推断
17184580 RGD
involved in positive regulation of cytosolic calcium ion concentration IDA
IDA: 通过直接分析推断
18082287 RGD
involved in positive regulation of fibroblast migration IDA
IDA: 通过直接分析推断
18475149 RGD
involved in positive regulation of fibroblast proliferation IDA
IDA: 通过直接分析推断
17184580 RGD
involved in positive regulation of heart rate IDA
IDA: 通过直接分析推断
12217424 RGD
involved in positive regulation of synaptic transmission, cholinergic IDA
IDA: 通过直接分析推断
15944374 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
16677483 RGD
involved in response to testosterone IEP
IEP: 通过表达模式推断
12421619 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
17184580 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
17184580 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

urotensin-2

U-II

UII

urocortin 2

urotensin II

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Uts2 NCBI NCBI:10911