1. Gene
  2. Ndst1 - N-deacetylase and N-sulfotransferase 1 Gene

Ndst1 - N-deacetylase and N-sulfotransferase 1 Gene

种属: Rattus norvegicus

同用名: Hsst; N-HSST

基因 ID: 29633 | 基因类型: protein coding

关于 Ndst1

功能概要

Enables [heparan sulfate]-glucosamine N-sulfotransferase activity and heparan sulfate N-deacetylase activity. Involved in heparan sulfate proteoglycan biosynthetic process. Predicted to be located in Golgi membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human NDST1 (N-deacetylase and N-sulfotransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

Ndst1 基因产物(1)

mRNA Protein Name
NM_024361.2 NP_077337.1 bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables [heparan sulfate]-glucosamine N-sulfotransferase activity IDA
IDA: 通过直接分析推断
1379236 RGD
enables heparan sulfate N-deacetylase activity IDA
IDA: 通过直接分析推断
8483907 RGD
enables heparan sulfate N-deacetylase activity IMP
IMP: 通过突变表型推断
9915799 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in heparan sulfate proteoglycan biosynthetic process IMP
IMP: 通过突变表型推断
9915799 RGD
involved in heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process IDA
IDA: 通过直接分析推断
1379236 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1

Golgi heparan sulfate N-deacetylase/N-sulfotransferase

HSNST 1

N-HSST 1

N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1

N-deacetylase/N-sulfotransferase 1

N-heparan sulfate sulfotransferase 1

NDST-1

[Heparan sulfate]-glucosamine N-sulfotr

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ndst1 NCBI NCBI:3340