2. Gene
  3. Ptpn5 - protein tyrosine phosphatase, non-receptor type 5 Gene

Ptpn5 - protein tyrosine phosphatase, non-receptor type 5 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: STEP

基因 ID: 29644 | 基因类型: protein coding

关于 Ptpn5

功能概要

Enables several functions, including identical protein binding activity; mitogen-activated protein kinase binding activity; and protein tyrosine Phosphatase activity. Involved in several processes, including positive regulation of cellular component organization; positive regulation of intracellular protein transport; and regulation of protein phosphorylation. Located in several cellular components, including perikaryon; proximal dendrite; and synaptic vesicle. Used to study transient cerebral ischemia. Biomarker of transient cerebral ischemia. Orthologous to human PTPN5 (protein tyrosine Phosphatase non-receptor type 5). [provided by Alliance of Genome Resources, Apr 2022]

Ptpn5 基因产物(1)

mRNA Protein Name
NM_001398605.1 NP_001385534.1 tyrosine-protein phosphatase non-receptor type 5
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
27103516 RGD
enables protein tyrosine phosphatase activity IDA
IDA: 通过直接分析推断
19625523 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in exploration behavior IDA
IDA: 通过直接分析推断
17008368 RGD
involved in negative regulation of MAP kinase activity IDA
IDA: 通过直接分析推断
9857190 RGD
involved in peptidyl-tyrosine dephosphorylation IDA
IDA: 通过直接分析推断
9857190 RGD
involved in positive regulation of long-term synaptic potentiation IMP
IMP: 通过突变表型推断
19026408 RGD
involved in positive regulation of neuron projection development IMP
IMP: 通过突变表型推断
10101226 RGD
involved in positive regulation of protein import into nucleus IMP
IMP: 通过突变表型推断
12483215 RGD
involved in positive regulation of protein phosphorylation IMP
IMP: 通过突变表型推断
19625523 RGD
involved in positive regulation of protein targeting to mitochondrion IMP
IMP: 通过突变表型推断
19625523 RGD
involved in positive regulation of receptor internalization IMP
IMP: 通过突变表型推断
19625523 RGD
involved in positive regulation of response to drug IMP
IMP: 通过突变表型推断
19026408 RGD
involved in regulation of neuron apoptotic process IMP
IMP: 通过突变表型推断
19625523 RGD
involved in response to amphetamine IEP
IEP: 通过表达模式推断
23711322 RGD
involved in response to immobilization stress IDA
IDA: 通过直接分析推断
17008368 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
17623046 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
7869116 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
8331384 RGD
located in perikaryon IDA
IDA: 通过直接分析推断
10101226 RGD
located in proximal dendrite IDA
IDA: 通过直接分析推断
8331384 RGD
located in synaptic membrane IDA
IDA: 通过直接分析推断
27103516 RGD
located in synaptic vesicle IDA
IDA: 通过直接分析推断
27103516 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

tyrosine-protein phosphatase non-receptor type 5

neural-specific protein-tyrosine phosphatase

protein-tyrosine phosphatase striatum-enriched

protein-tyrosine-phosphatase non-receptor 5

striatum-enriched protein-tyrosine phosphatase

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-141800 MurA-IN-1 Inhibitor 99.32% 否
HY-155847 LYP-IN-3 99.80% 否
HY-RS11428 PTPN5 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20091 Ptpn5 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26594 Ptpn5 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ptpn5 NCBI NCBI:84867
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