1. Gene
  2. Adamts8 - a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8 Gene

Adamts8 - a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8 Gene

种属: Mus musculus

同用名: METH2; METH-2

基因 ID: 30806 | 基因类型: protein coding

关于 Adamts8

功能概要

This gene encodes a member of "a disintegrin and metalloproteinase with thrombospondin motifs" (ADAMTS) family of multi-domain matrix-associated metalloendopeptidases that have diverse roles in tissue morphogenesis and pathophysiological remodeling, in inflammation and in vascular biology. This gene is expressed in mouse lung, heart and macrophage-rich areas of atherosclerotic plaques. The encoded preproprotein undergoes proteolytic processing to generate an active, zinc-dependent aggrecanase enzyme. This gene is located adjacent to a related ADAMTS gene on chromosome 9. [provided by RefSeq, May 2016]

Adamts8 基因产物(2)

mRNA Protein Name
NM_001326292.1 NP_001313221.1 A disintegrin and metalloproteinase with thrombospondin motifs 8 isoform 2
NM_013906.3 NP_038934.2 A disintegrin and metalloproteinase with thrombospondin motifs 8 isoform 1 preproprotein
蛋白主名 其他名称

A disintegrin and metalloproteinase with thrombospondin motifs 8

a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Adamts8 NCBI NCBI:11095