1. Gene
  2. Sphk2 - sphingosine kinase 2 Gene

Sphk2 - sphingosine kinase 2 Gene

中文名称:鞘氨醇激酶 2

种属: Rattus norvegicus

基因 ID: 308589 | 基因类型: protein coding

关于 Sphk2

Primary_assembly 1: 96,180,887-96,188,391 reverse strand.mRatBN7.2:CM026974.1

This gene has 1 transcript (splice variant), 209 orthologues, 4 paralogues and is associated with 3 phenotypes. Biased expression in Kidney (RPKM 86.5), Adrenal (RPKM 75.8) and 9 other tissues.

功能概要

预测该基因编码的蛋白可启动激酶活性;核小体组蛋白结合活性;和 1- 磷酸鞘氨醇受体活性。参与女性妊娠。预计位于多个细胞成分中,包括内质网;线粒体内膜;和核质。预计是核小体的一部分。预计在细胞质中有活性;细胞内膜结合细胞器;和膜。与人 SPHK2(鞘氨醇激酶 2)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable kinase activity; nucleosomal histone binding activity; and sphingosine-1-phosphate receptor activity. Involved in female pregnancy. Predicted to be located in several cellular components, including endoplasmic reticulum; mitochondrial inner membrane; and nucleoplasm. Predicted to be part of nucleosome. Predicted to be active in cytoplasm; intracellular membrane-bounded organelle; and membrane. Orthologous to human SphK2 (sphingosine kinase 2). [provided by Alliance of Genome Resources, Apr 2022]

Sphk2 基因产物(1)

mRNA Protein Name
NM_001012066.1 NP_001012066.1 sphingosine kinase 2
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in female pregnancy IEP
IEP: 通过表达模式推断
18723875 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Sphk2 蛋白结构

PLN02958

PLN02958: cl29912 (151 - 606)

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  • 616 a.a.
蛋白主名 其他名称

sphingosine kinase 2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sphk2 NCBI NCBI:56848