2. Gene
  3. Zeb2 - zinc finger E-box binding homeobox 2 Gene

Zeb2 - zinc finger E-box binding homeobox 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Zfhx1b

基因 ID: 311071 | 基因类型: protein coding

关于 Zeb2

功能概要

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; R-SMAD binding activity; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including melanocyte migration; positive regulation of cell differentiation; and positive regulation of signal transduction. Predicted to act upstream of or within several processes, including nervous system development; neural crest cell migration; and positive regulation of signal transduction. Predicted to be located in chromatin; cytosol; and nuclear lumen. Human ortholog(s) of this gene implicated in Hirschsprung's disease and Mowat-Wilson syndrome. Orthologous to human ZEB2 (zinc finger E-box binding homeobox 2). [provided by Alliance of Genome Resources, Apr 2022]

Zeb2 基因产物(1)

mRNA Protein Name
NM_001033701.2 NP_001028873.2 zinc finger E-box-binding homeobox 2
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in astrocyte activation IDA
IDA: 通过直接分析推断
34852714 RGD
involved in endothelial cell migration IMP
IMP: 通过突变表型推断
31881206 RGD
involved in endothelial cell proliferation IMP
IMP: 通过突变表型推断
31881206 RGD
involved in fibroblast activation IDA
IDA: 通过直接分析推断
30336567 RGD
involved in myofibroblast differentiation IEP
IEP: 通过表达模式推断
24155330 RGD
involved in negative regulation of fibroblast migration IDA
IDA: 通过直接分析推断
30336567 RGD
involved in positive regulation of myofibroblast contraction IDA
IDA: 通过直接分析推断
30336567 RGD
involved in pyroptotic inflammatory response IDA
IDA: 通过直接分析推断
34852714 RGD
involved in regulation of blood-brain barrier permeability IMP
IMP: 通过突变表型推断
34334113 RGD
involved in regulation of myofibroblast cell apoptotic process IMP
IMP: 通过突变表型推断
34321385 RGD
involved in response to oxygen-glucose deprivation IMP
IMP: 通过突变表型推断
34321385 RGD
involved in stress fiber assembly IMP
IMP: 通过突变表型推断
31784544 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

zinc finger E-box-binding homeobox 2

zinc finger homeobox 1b

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-131445 RJW100 Activator 99.93% 否
HY-173557 PRMT7-IN-2 98.26% 否
HY-RS17821 Zeb2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16026 ZEB2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24289 Zeb2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Zeb2 NCBI NCBI:9839
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