2. Gene
  3. Traf2 - Tnf receptor-associated factor 2 Gene

Traf2 - Tnf receptor-associated factor 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 311786 | 基因类型: protein coding

关于 Traf2

功能概要

Enables mitogen-activated protein kinase kinase kinase binding activity. Involved in negative regulation of glial cell apoptotic process; positive regulation of NF-kappaB transcription factor activity; and tumor necrosis factor-mediated signaling pathway. Located in cell cortex and membrane raft. Part of protein-containing complex. Orthologous to human TRAF2 (TNF Receptor associated factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Traf2 基因产物(1)

mRNA Protein Name
NM_001107815.2 NP_001101285.1 TNF receptor-associated factor 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables mitogen-activated protein kinase kinase kinase binding IPI
IPI: 通过物理相互作用推断
12050113 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
12786973 RGD
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
10650002 RGD
enables protein-containing complex binding IPI
IPI: 通过物理相互作用推断
12786973 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of glial cell apoptotic process IMP
IMP: 通过突变表型推断
9813034 RGD
involved in positive regulation of NF-kappaB transcription factor activity IMP
IMP: 通过突变表型推断
10713108 RGD
involved in tumor necrosis factor-mediated signaling pathway IMP
IMP: 通过突变表型推断
10713108 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell cortex IDA
IDA: 通过直接分析推断
12786973 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
12786973 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

TNF receptor-associated factor 2

相关产品

Approval
生物活性分子 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-19696B Tauroursodeoxycholate dihydrate 99.96% 是
Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-16591 Birinapant 99.70% Phase 2
Pre-clinical Phase
生物活性分子 (19)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-100830 NCB-0846 Inhibitor 99.61% 否
HY-138779 ICCB-19 hydrochloride 99.25% 否
HY-134050 Apostatin-1 99.64% 否
HY-124745 KY-05009 99.88% 否
HY-117469 Triptohypol C 96.56% 否
HY-153598 LD4172 98.32% 否
HY-145293 TNIK-IN-3 Inhibitor 99.79% 否
HY-124762 TNIK-IN-1 Inhibitor 98.86% 否
HY-156502 TINK-IN-1 Inhibitor 98.02% 否
HY-156818 TNIK-IN-7 Inhibitor 99.90% 否
HY-100830A NCB-0970 Control 98.81% 否
HY-156817 TNIK-IN-6 Inhibitor 96.92% 否
HY-122805 PF-794 Inhibitor 99.19% 否
HY-145292 TNIK-IN-2 Inhibitor 99.68% 否
HY-RS14197 TANK Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS14968 TRAF2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-174514 Human TNFRSF4 mRNA / 否
HY-RS16859 Traf2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23300 Traf2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Traf2 NCBI NCBI:7186
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