2. Gene
  3. Kdm5a - lysine demethylase 5A Gene

Kdm5a - lysine demethylase 5A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Jarid1a

基因 ID: 312678 | 基因类型: protein coding

关于 Kdm5a

功能概要

Predicted to enable several functions, including DNA binding activity; histone H3-tri/di/monomethyl-lysine-4 demethylase activity; and zinc ion binding activity. Involved in histone H3-K4 demethylation; male gonad development; and spermatogenesis. Predicted to be part of protein-DNA complex. Predicted to be active in nucleus. Biomarker of cryptorchidism. Human ortholog(s) of this gene implicated in ankylosing spondylitis. Orthologous to human KDM5A (lysine demethylase 5A). [provided by Alliance of Genome Resources, Apr 2022]

Kdm5a 基因产物(2)

mRNA Protein Name
NM_001277177.1 NP_001264106.1 lysine-specific demethylase 5A isoform 1
NM_001277178.1 NP_001264107.1 lysine-specific demethylase 5A isoform 2
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in male gonad development IEP
IEP: 通过表达模式推断
24679876 RGD
involved in protein modification process IEP
IEP: 通过表达模式推断
24679876 RGD
involved in spermatogenesis IEP
IEP: 通过表达模式推断
24679876 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

lysine-specific demethylase 5A

jumonji, AT rich interactive domain 1A (Rbp2 like)

lysine (K)-specific demethylase 5A

相关产品

Pre-clinical Phase
生物活性分子 (17)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-100421 CPI-455 Inhibitor 98.95% 否
HY-102047B KDOAM-25 citrate Inhibitor 98.56% 否
HY-100014 KDM5A-IN-1 Inhibitor 99.64% 否
HY-107573 KDM2/7-IN-1 Inhibitor 99.9% 否
HY-119397A KDM5-C49 hydrochloride Inhibitor 98.22% 否
HY-100421A CPI-455 hydrochloride Inhibitor 99.95% 否
HY-100624 Ryuvidine Inhibitor 99.23% 否
HY-100764 YUKA1 Inhibitor 99.15% 否
HY-144501 D18 98.79% 否
HY-123419 CPI-4203 Inhibitor 99.0% 否
HY-102047 KDOAM-25 Inhibitor / 否
HY-RS07218 KDM5A Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-102047A KDOAM-25 trihydrochloride Inhibitor / 否
HY-119397 KDM5-C49 Inhibitor / 否
HY-136682 N19-0881 Inhibitor / 否
HY-RS16664 Kdm5a Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23099 Kdm5a Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Kdm5a NCBI NCBI:5927
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