Trim32 - tripartite motif-containing 32 Gene

种属: Rattus norvegicus

关于 Trim32

功能概要

Predicted to enable several functions, including identical protein binding activity; ubiquitin binding activity; and ubiquitin protein Ligase activity. Predicted to be involved in several processes, including defense response to Other organism; positive regulation of protein metabolic process; and regulation of intracellular signal transduction. Predicted to act upstream of or within several processes, including muscle cell cellular homeostasis; positive regulation of cytokine-mediated signaling pathway; and protein ubiquitination. Predicted to be located in nucleus and striated muscle Myosin thick filament. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome; Bardet-Biedl syndrome 11; autosomal recessive limb-girdle muscular dystrophy type 2H; and muscular dystrophy. Orthologous to human TRIM32 (tripartite motif containing 32). [provided by Alliance of Genome Resources, Apr 2022]