1. Gene
  2. Errfi1 - ERBB receptor feedback inhibitor 1 Gene

Errfi1 - ERBB receptor feedback inhibitor 1 Gene

种属: Rattus norvegicus

同用名: Xxx; Ralt; gene 33; RGD1307599

基因 ID: 313729 | 基因类型: protein coding

关于 Errfi1

功能概要

Enables SH3 domain binding activity; kinase binding activity; and small GTPase binding activity. Involved in several processes, including cellular response to growth factor stimulus; cellular response to hormone stimulus; and negative regulation of macromolecule metabolic process. Located in cytosol and plasma membrane. Orthologous to human ERRFI1 (ERBB receptor feedback inhibitor 1). [provided by Alliance of Genome Resources, Apr 2022]

Errfi1 基因产物(1)

mRNA Protein Name
NM_001014071.1 NP_001014093.1 ERBB receptor feedback inhibitor 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables SH3 domain binding IDA
IDA: 通过直接分析推断
11003669 RGD
enables kinase binding IPI
IPI: 通过物理相互作用推断
17599051 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
10749885 RGD
enables small GTPase binding IPI
IPI: 通过物理相互作用推断
10749885 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular hyperosmotic response IEP
IEP: 通过表达模式推断
10749885 RGD
involved in cellular response to dexamethasone stimulus IEP
IEP: 通过表达模式推断
23384834 RGD
involved in cellular response to epidermal growth factor stimulus IEP
IEP: 通过表达模式推断
15556944 RGD
involved in cellular response to insulin stimulus IEP
IEP: 通过表达模式推断
15358516 RGD
involved in cellular response to platelet-derived growth factor stimulus IEP
IEP: 通过表达模式推断
15556944 RGD
involved in negative regulation of ERK1 and ERK2 cascade IDA
IDA: 通过直接分析推断
19204184 RGD
involved in negative regulation of cardiac muscle hypertrophy in response to stress IDA
IDA: 通过直接分析推断
19204184 RGD
involved in negative regulation of collagen biosynthetic process IMP
IMP: 通过突变表型推断
19204184 RGD
involved in negative regulation of epidermal growth factor receptor signaling pathway IMP
IMP: 通过突变表型推断
19204184 RGD
involved in negative regulation of epidermal growth factor-activated receptor activity IDA
IDA: 通过直接分析推断
17599051 RGD
involved in negative regulation of interleukin-1 beta production IMP
IMP: 通过突变表型推断
19204184 RGD
involved in negative regulation of peptidyl-tyrosine phosphorylation IDA
IDA: 通过直接分析推断
17599051 RGD
involved in negative regulation of tumor necrosis factor production IMP
IMP: 通过突变表型推断
19204184 RGD
involved in regulation of type B pancreatic cell proliferation IMP
IMP: 通过突变表型推断
23384834 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

ERBB receptor feedback inhibitor 1

gene 33 polypeptide

mig-6

mitogen-inducible gene 6 protein homolog

receptor-associated late transducer

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Errfi1 NCBI NCBI:54206