2. Gene
  3. Rc3h2 - ring finger and CCCH-type zinc finger domains 2 Gene

Rc3h2 - ring finger and CCCH-type zinc finger domains 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Mnab; Rnf164; 2900024N03Rik; 9430019J22Rik; D930043C02Rik

基因 ID: 319817 | 基因类型: protein coding

关于 Rc3h2

功能概要

Enables mRNA binding activity. Involved in T cell receptor signaling pathway; negative regulation of T-helper 17 cell differentiation; and regulation of miRNA metabolic process. Acts upstream of or within several processes, including hematopoietic or lymphoid organ development; lymphocyte homeostasis; and positive regulation of NIK/NF-kappaB signaling. Predicted to be located in cell surface; intracellular membrane-bounded organelle; and membrane. Predicted to be active in cytoplasmic stress granule. Orthologous to human RC3H2 (ring finger and CCCH-type domains 2). [provided by Alliance of Genome Resources, Apr 2022]

Rc3h2 基因产物(2)

mRNA Protein Name
NM_001100591.1 NP_001094061.1 roquin-2 isoform a
NM_001290642.1 NP_001277571.1 roquin-2 isoform b
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables mRNA binding IDA
IDA: 通过直接分析推断
23583643 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
23583643 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within B cell homeostasis IGI
IGI: 通过遗传相互作用推断
23583643 MGI
acts upstream of or within T cell homeostasis IGI
IGI: 通过遗传相互作用推断
23583643 MGI
acts upstream of or within T cell proliferation IGI
IGI: 通过遗传相互作用推断
23583643 MGI
involved in T cell receptor signaling pathway IMP
IMP: 通过突变表型推断
25282160 MGI
acts upstream of or within T follicular helper cell differentiation IGI
IGI: 通过遗传相互作用推断
23583643 MGI
acts upstream of or within limb development IMP
IMP: 通过突变表型推断
23583643 MGI
acts upstream of or within lung alveolus development IMP
IMP: 通过突变表型推断
23583643 MGI
acts upstream of or within lymph node development IGI
IGI: 通过遗传相互作用推断
23583643 MGI
acts upstream of or within multicellular organism growth IMP
IMP: 通过突变表型推断
23583643 MGI
involved in negative regulation of T-helper 17 cell differentiation IMP
IMP: 通过突变表型推断
25282160 MGI
acts upstream of or within positive regulation of non-canonical NF-kappaB signal transduction IDA
IDA: 通过直接分析推断
23583643 MGI
acts upstream of or within post-embryonic development IMP
IMP: 通过突变表型推断
23583643 MGI
acts upstream of or within post-transcriptional regulation of gene expression IDA
IDA: 通过直接分析推断
23583643 MGI
acts upstream of or within regulation of gene expression IDA
IDA: 通过直接分析推断
23583643 MGI
involved in regulation of miRNA metabolic process IMP
IMP: 通过突变表型推断
25697406 MGI
acts upstream of or within spleen development IGI
IGI: 通过遗传相互作用推断
23583643 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

roquin-2

RING-type E3 ubiquitin transferase Roquin-2

membrane associated DNA binding protein

membrane-associated nucleic acid binding protein

ring finger and CCCH-type zinc finger domain-containing protein 2

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11778 RC3H2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21727 Rc3h2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28244 Rc3h2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rc3h2 NCBI NCBI:54542
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