2. Gene
  3. Dgki - diacylglycerol kinase, iota Gene

Dgki - diacylglycerol kinase, iota Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: 6430604M11Rik; C130010K08Rik

基因 ID: 320127 | 基因类型: protein coding

关于 Dgki

功能概要

Enables GTPase inhibitor activity; diacylglycerol kinase activity; and small GTPase binding activity. Involved in regulation of synaptic vesicle exocytosis. Acts upstream of or within several processes, including chemical synaptic transmission; habituation; and modulation of chemical synaptic transmission. Located in Schaffer collateral - CA1 synapse; glutamatergic synapse; and perinuclear region of cytoplasm. Part of guanyl-nucleotide exchange factor complex. Is expressed in cerebral cortex; cerebral cortex mantle layer; and cerebral cortex marginal layer. Orthologous to human DGKI (diacylglycerol kinase iota). [provided by Alliance of Genome Resources, Apr 2022]

Dgki 基因产物(2)

mRNA Protein Name
NM_001081206.2 NP_001074675.1 diacylglycerol kinase iota isoform 1
NM_001347104.2 NP_001334033.1 diacylglycerol kinase iota isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATP-dependent diacylglycerol kinase activity IDA
IDA: 通过直接分析推断
15894621 MGI
enables GTPase inhibitor activity IDA
IDA: 通过直接分析推断
15894621 MGI
enables GTPase inhibitor activity IMP
IMP: 通过突变表型推断
15894621 MGI
enables small GTPase binding IPI
IPI: 通过物理相互作用推断
15894621 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of Ras protein signal transduction IMP
IMP: 通过突变表型推断
15894621 MGI
acts upstream of or within excitatory postsynaptic potential IMP
IMP: 通过突变表型推断
21119615 MGI
acts upstream of or within habituation IMP
IMP: 通过突变表型推断
21119615 MGI
acts upstream of or within neurotransmitter secretion IMP
IMP: 通过突变表型推断
21119615 MGI
acts upstream of or within positive regulation of Ras protein signal transduction IMP
IMP: 通过突变表型推断
15894621 MGI
involved in presynaptic modulation of chemical synaptic transmission IDA
IDA: 通过直接分析推断
21119615 MGI
involved in presynaptic modulation of chemical synaptic transmission IMP
IMP: 通过突变表型推断
21119615 MGI
acts upstream of or within regulation of GTPase activity IMP
IMP: 通过突变表型推断
15894621 MGI
acts upstream of or within regulation of long-term synaptic depression IMP
IMP: 通过突变表型推断
21119615 MGI
acts upstream of or within regulation of synaptic transmission, glutamatergic IMP
IMP: 通过突变表型推断
21119615 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in Schaffer collateral - CA1 synapse IDA
IDA: 通过直接分析推断
21119615 MGI
is active in Schaffer collateral - CA1 synapse IMP
IMP: 通过突变表型推断
21119615 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
15894621 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
21119615 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
21119615 MGI
part of guanyl-nucleotide exchange factor complex IDA
IDA: 通过直接分析推断
15894621 MGI
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
15894621 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

diacylglycerol kinase iota

DAG kinase iota

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03721 DGKI Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22136 Dgki Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28657 Dgki Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dgki NCBI NCBI:9162
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