2. Gene
  3. Pkn1 - protein kinase N1 Gene

Pkn1 - protein kinase N1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: DBK; Pkn; PAK1; PRK1; Stk3; Prkcl1; F730027O18Rik

基因 ID: 320795 | 基因类型: protein coding

关于 Pkn1

功能概要

Enables protein kinase activity. Acts upstream of or within several processes, including negative regulation of B cell proliferation; regulation of germinal center formation; and spleen development. Located in cytoplasmic vesicle. Is expressed in several structures, including brown fat; genitourinary system; gut; nervous system; and vascular system. Orthologous to human PKN1 (protein kinase N1). [provided by Alliance of Genome Resources, Apr 2022]

Pkn1 基因产物(2)

mRNA Protein Name
NM_001199593.1 NP_001186522.1 serine/threonine-protein kinase N1 isoform 1
NM_177262.4 NP_796236.2 serine/threonine-protein kinase N1 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
11054541 MGI
enables protein kinase activity IMP
IMP: 通过突变表型推断
12783890 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within B cell apoptotic process IMP
IMP: 通过突变表型推断
23223530 MGI
acts upstream of or within B cell homeostasis IMP
IMP: 通过突变表型推断
23223530 MGI
acts upstream of or within hyperosmotic response IDA
IDA: 通过直接分析推断
12783890 MGI
acts upstream of or within negative regulation of B cell proliferation IMP
IMP: 通过突变表型推断
23223530 MGI
acts upstream of or within negative regulation of protein kinase activity IMP
IMP: 通过突变表型推断
23223530 MGI
acts upstream of or within negative regulation of protein phosphorylation IMP
IMP: 通过突变表型推断
23223530 MGI
acts upstream of or within regulation of germinal center formation IMP
IMP: 通过突变表型推断
23223530 MGI
acts upstream of or within regulation of immunoglobulin production IMP
IMP: 通过突变表型推断
23223530 MGI
acts upstream of or within renal system process IMP
IMP: 通过突变表型推断
23223530 MGI
acts upstream of or within spleen development IMP
IMP: 通过突变表型推断
23223530 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
12783890 MGI
located in cytoplasmic vesicle IDA
IDA: 通过直接分析推断
12783890 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

serine/threonine-protein kinase N1

protein kinase C-like 1

protein kinase C-like PKN

protein-kinase C-related kinase 1

serine-threonine protein kinase N

serine/threonine kinase 3

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-145899 PKN1/2-IN-1 Inhibitor 99.92% 否
HY-RS10606 PKN1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19934 Pkn1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26436 Pkn1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pkn1 NCBI NCBI:5585
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