2. Gene
  3. Dna2 - DNA replication helicase/nuclease 2 Gene

Dna2 - DNA replication helicase/nuclease 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Dna2l; E130315B21Rik

基因 ID: 327762 | 基因类型: protein coding

关于 Dna2

功能概要

Enables 5'-flap Endonuclease activity. Involved in mitotic telomere maintenance via semi-conservative replication and nucleic acid phosphodiester bond hydrolysis. Located in chromosome, telomeric region. Human ortholog(s) of this gene implicated in Seckel syndrome 8; autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 6; isolated growth hormone deficiency type IA; and mitochondrial myopathy. Orthologous to human DNA2 (DNA replication helicase/nuclease 2). [provided by Alliance of Genome Resources, Apr 2022]

Dna2 基因产物(1)

mRNA Protein Name
NM_177372.3 NP_796346.2 DNA replication ATP-dependent helicase/nuclease DNA2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 5'-flap endonuclease activity IDA
IDA: 通过直接分析推断
23604072 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
23604072 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in mitotic telomere maintenance via semi-conservative replication IMP
IMP: 通过突变表型推断
23604072 MGI
involved in nucleic acid metabolic process IDA
IDA: 通过直接分析推断
23604072 MGI
involved in telomere maintenance IMP
IMP: 通过突变表型推断
23604072 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in chromosome, telomeric region IDA
IDA: 通过直接分析推断
23604072 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

DNA replication ATP-dependent helicase/nuclease DNA2

DNA replication ATP-dependent helicase-like homolog

DNA replication helicase 2 homolog

DNA2-like helicase

相关产品

Pre-clinical Phase
生物活性分子 (28)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-107999 CADD522 Agonist 98.23% 否
HY-128729 DNA2 inhibitor C5 Inhibitor 98.51% 否
HY-124838 EG1 98.26% 否
HY-126861 2'-Deoxy-5-formylcytidine 99.70% 否
HY-W016009 2'-Deoxyadenosine-5'-monophosphate 99.60% 否
HY-W039442 2′-Deoxy-2′-fluoroadenosine 99.71% 否
HY-135009 2-Di-1-ASP 99.97% 否
HY-155339 Anticancer agent 168 99.55% 否
HY-W020086 2,3-Diaminophenazine 99.84% 否
HY-W016009R 2'-Deoxyadenosine-5'-monophosphate (Standard) 99.15% 否
HY-W008598 2-Bromo-4'-fluoroacetophenone Inhibitor 99.15% 否
HY-W105272 2′-Deoxyadenosine 5′-monophosphate disodium 99.31% 否
HY-160839 SPB-PEG4-AAD / 否
HY-160840 SPB-AAD / 否
HY-W105272S 2′-Deoxyadenosine 5′-monophosphate-13C10,15N5 disodium 99.8% 否
HY-W016009S 2'-Deoxyadenosine-5'-monophosphate-d12 dilithium 97.7% 否
HY-128729R DNA2 inhibitor C5 (Standard) Inhibitor 97.58% 否
HY-RS03838 DNA2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-W013059S1 DMT-dA(bz) Phosphoramidite-15N5 / 否
HY-W013068S1 DMT-dT Phosphoramidite-15N2 / 否
HY-W016009S1 2'-Deoxyadenosine-5'-monophosphate-15N5,d12 dilithium / 否
HY-W016009S2 2'-Deoxyadenosine-5'-monophosphate-15N5 dilithium / 否
HY-W016009S3 2'-Deoxyadenosine-5'-monophosphate-13C10 dilithium / 否
HY-W016009S4 2'-Deoxyadenosine-5'-monophosphate-13C10,15N5 dilithium / 否
HY-RS19320 Dna2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25811 Dna2 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-W013059S DMT-dA(bz) Phosphoramidite-13C10,15N5 / 否
HY-W013068S DMT-dT Phosphoramidite-13C10,15N2 / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dna2 NCBI NCBI:1763
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z