2. Gene
  3. CTU2 - cytosolic thiouridylase subunit 2 Gene

CTU2 - cytosolic thiouridylase subunit 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：胞质硫尿苷酶亚基 2

种属: Homo sapiens

同用名: MFRG; NCS2; UPF0432; C16orf84

基因 ID: 348180 | 基因类型: protein coding

关于 CTU2

Cytogenetic location: 16q24.3 Genomic coordinates (GRCh38): 16:88,706,503-88,715,396 (from NCBI)

This gene has 10 transcripts (splice variants), 193 orthologues and is associated with 2 phenotypes. Ubiquitous expression in testis (RPKM 3.9), brain (RPKM 2.8) and 25 other tissues.

功能概要

该基因编码一种蛋白质，该蛋白质参与转移 RNA (tRNA) 的转录后修饰。编码的蛋白质在存在于 tRNA 子集中摆动位置的尿苷残基的硫醇化中发挥作用，从而提高密码子读取准确性。可变剪接导致编码不同异构体的多个转录变体。[RefSeq 提供，2016 年 1 月]

This gene encodes a protein which is involved in the post-transcriptional modification of transfer RNAs (tRNAs). The encoded protein plays a role in thiolation of uridine residue present at the wobble position in a subset of tRNAs, resulting in enhanced codon reading accuracy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]

CTU2 基因产物(4)

mRNA Protein Name
NM_001012759.3 NP_001012777.1 cytoplasmic tRNA 2-thiolation protein 2 isoform 1
NM_001012762.3 NP_001012780.1 cytoplasmic tRNA 2-thiolation protein 2 isoform 2
NM_001318507.2 NP_001305436.1 cytoplasmic tRNA 2-thiolation protein 2 isoform 3
NM_001318513.2 NP_001305442.1 cytoplasmic tRNA 2-thiolation protein 2 isoform 4

CTU2 蛋白结构

CTU2

CTU2: Cytoplasmic tRNA 2-thiolation protein 2 (271 - 371)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 515 a.a.
蛋白主名 其他名称

cytoplasmic tRNA 2-thiolation protein 2

cytosolic thiouridylase subunit 2 homolog

CTU2 抗体

目录号 产品名 应用 反应物种
HY-P86828 CTU2 Antibody (YA6521) WB, IHC-P Human, Mouse, Monkey

关联疾病

疾病名称 别名
Microcephaly, Facial Dysmorphism, Renal Agenesis, And Ambiguous Genitalia Syndrome

MFRG
Peroneal Neuropathy

Peroneal Neuropathies
Cakut

Renal Or Urinary Tract Malformation

Congenital Anomalies Of Kidney And Urinary Tract

Congenital Anomaly Of Kidney And Urinary Tract

Congenital Anomalies Of The Kidney And Urinary Tract

Kidney And Urinary Tract, Anomalies, Congenital

Renal Hypodysplasia, Nonsyndromic, 1
Phobia, Specific

Specific Phobia

Simple Phobia

Phobia, Simple

Isolated Phobia
Primary Microcephaly

True Microcephaly

Microcephaly, Primary
Dysthymic Disorder

Dysthymia

Chronic Depressive Disorder

Chronic Depression

Depressive Personality

Depressive Personality Disorder

Persistent Depressive Disorder

Persistent Depression
Social Phobia

Phobia, Social

Phobia Social

Phobic Anxiety Disorder
Intermittent Explosive Disorder

Explosive Personality Disorder
Phobic Disorder

Phobic Disorders

Phobic Anxiety Disorder
Sucrase-Isomaltase Deficiency, Congenital

Congenital Sucrase-Isomaltase Deficiency

CSID

Si Deficiency

Congenital Sucrose Intolerance

Disaccharide Intolerance

Sucrase-Isomaltase Deficiency

Disaccharide Intolerance I

Congenital Sucrose-Isomaltose Malabsorption

Sucrose-Isomaltose Malabsorption, Congenital

Sucrose Intolerance, Congenital

Congenital Sucrase-Isomaltose Malabsorption

Congenital Sucrose-Isomaltase Malabsorption

Disaccharide Intolerance, 1

Sucrose Intolerance Congenital

Sucrose-Isomaltase Malabsorption, Congenital

Disaccharidase Deficiency

Invertase Deficiency

Sucrase-Alpha-Dextrinase Deficiency

Disaccharide Intolerance Type I

Csid - [Congenital Sucrase-Isomaltase Deficiency]

Sucrose Intolerance Of Newborn

Sucrose Intolerance

Sucrase Deficiency

Disaccharide Malabsorption

Intestinal Disaccharidase Deficiency
Hymenolepiasis

Dwarf Tapeworm Infection

Hymenolepis Infectious Disease

Hymenolepsis Infection

Hyemolepis Nana Infection

Hymenolepiosis

Hymenolepis Infection

Dwarf Tapeworm

Hymenolepidosis

Hymenolepis Infestation
Agoraphobia

Fear Of Open Spaces

Phobia Of Going Out
Separation Anxiety Disorder

Separation Anxiety Disorder Of Childhood
Generalized Anxiety Disorder

Anxiety Generalized
Lissencephaly

Pachygyria

Broad Gyri Of Cerebrum

Large Gyri Of Cerebrum

Macrogyria
Kbg Syndrome

KBGS

Macrodontia, Mental Retardation, Characteristic Facies, Short Stature, And Skeletal Anomalies

Short Stature, Characteristic Facies, Macrodontia, Intellectual Disability, And Skeletal Anomalies

Short Stature, Characteristic Facies, Macrodontia, Mental Retardation, And Skeletal Anomalies

Short Stature-Characteristic Facies-Mental Retardation-Macrodontia-Skeletal Anomalies Syndrome

Short Stature-Facial And Skeletal Anomalies-Intellectual Disability-Macrodontia Syndrome
Microcephaly

Microencephaly

Microcephalus

Microcephalic

Nanocephaly

Congenital Microcephaly

Brain Hypoplasia

Brain Nondevelopment

Cephalic Hypoplasia

Undeveloped Cerebrum

Undeveloped Brain

Micrencephalon

Micrencephaly
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03354 CTU2 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus CTU2 RGD RGD:1562594
Mus musculus CTU2 MGD MGI:1914215
Felis catus CTU2 VGNC VGNC:61276
Canis familiaris CTU2 VGNC VGNC:39721
Bos taurus CTU2 VGNC VGNC:27824
Macaca mulatta CTU2 VGNC VGNC:71598
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