2. Gene
  3. Slit2 - slit guidance ligand 2 Gene

Slit2 - slit guidance ligand 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 360272 | 基因类型: protein coding

关于 Slit2

功能概要

Enables heparan sulfate proteoglycan binding activity. Involved in several processes, including central nervous system development; negative regulation of inflammatory response; and negative regulation of monocyte chemotaxis. Located in plasma membrane. Biomarker of anti-basement membrane glomerulonephritis. Orthologous to human SLIT2 (slit guidance ligand 2). [provided by Alliance of Genome Resources, Apr 2022]

Slit2 基因产物(1)

mRNA Protein Name
NM_022632.2 NP_072154.2 slit homolog 2 protein precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables heparan sulfate proteoglycan binding IDA
IDA: 通过直接分析推断
10364234 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
15528323 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to hypoxia IEP
IEP: 通过表达模式推断
26764532 RGD
involved in cellular response to platelet-derived growth factor stimulus IEP
IEP: 通过表达模式推断
21315131 RGD
involved in negative regulation of monocyte chemotaxis IDA
IDA: 通过直接分析推断
15528323 RGD
involved in neuron projection extension IMP
IMP: 通过突变表型推断
26738857 RGD
involved in positive regulation of synapse assembly IMP
IMP: 通过突变表型推断
26738857 RGD
involved in response to nutrient levels IEP
IEP: 通过表达模式推断
16497807 RGD
involved in spinal cord development IEP
IEP: 通过表达模式推断
10102268 RGD
involved in synapse maturation IDA
IDA: 通过直接分析推断
34686348 RGD
involved in synapse maturation IMP
IMP: 通过突变表型推断
34686348 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
26738857 RGD
located in cell body IDA
IDA: 通过直接分析推断
27686659 RGD
located in cell projection IDA
IDA: 通过直接分析推断
27686659 RGD
located in dendrite IDA
IDA: 通过直接分析推断
26738857 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
26738857 RGD
is active in perisynaptic extracellular matrix EXP
EXP: 通过实验结果推断
34686348 RGD
is active in perisynaptic extracellular matrix IDA
IDA: 通过直接分析推断
34686348 RGD
is active in perisynaptic extracellular matrix IMP
IMP: 通过突变表型推断
34686348 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

slit homolog 2 protein

slit-2

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-175200 DEL-S1 98.01% 否
HY-146411 microRNA-21-IN-1 98.03% 否
HY-RS13371 SLIT2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS13372 SLIT3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19035 Slit2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25524 Slit2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Slit2 NCBI NCBI:9353
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