Atg16l1 - autophagy related 16-like 1 Gene

种属: Rattus norvegicus

同用名: Wdr30; Apg16l

关于 Atg16l1

功能概要

Predicted to enable GTPase binding activity and identical protein binding activity. Predicted to be involved in autophagosome assembly; negative stranded viral RNA replication; and positive regulation of Autophagy. Predicted to act upstream of or within protein lipidation involved in autophagosome assembly; protein localization to phagophore assembly site; and xenophagy. Predicted to be located in autophagosome; axoneme; and vacuole-isolation membrane contact site. Predicted to be active in autophagosome membrane. Human ortholog(s) of this gene implicated in inflammatory bowel disease 10. Orthologous to human ATG16L1 (Autophagy related 16 like 1). [provided by Alliance of Genome Resources, Apr 2022]