1. Gene
  2. Flrt3 - fibronectin leucine rich transmembrane protein 3 Gene

Flrt3 - fibronectin leucine rich transmembrane protein 3 Gene

种属: Rattus norvegicus

同用名: RGD1566005

基因 ID: 366205 | 基因类型: protein coding

关于 Flrt3

功能概要

Predicted to enable chemorepellent activity; Fibroblast Growth Factor receptor binding activity; and protein homodimerization activity. Involved in neuron projection extension; response to axon injury; and synapse organization. Acts upstream of or within axon guidance. Located in axon terminus; postsynaptic density; and synaptic membrane. Is integral component of postsynaptic membrane. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 21 with or without anosmia. Orthologous to human FLRT3 (fibronectin leucine rich transmembrane protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Flrt3 基因产物(1)

mRNA Protein Name
NM_001126291.1 NP_001119763.1 leucine-rich repeat transmembrane protein FLRT3 precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within axon guidance IGI
IGI: 通过遗传相互作用推断
21673655 RGD
involved in neuron projection development IMP
IMP: 通过突变表型推断
15485775 RGD
involved in neuron projection extension IMP
IMP: 通过突变表型推断
15485775 RGD
involved in response to axon injury IMP
IMP: 通过突变表型推断
15485775 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon terminus IDA
IDA: 通过直接分析推断
15485775 RGD
located in plasma membrane IDA
IDA: 通过直接分析推断
15485775 RGD
located in synaptic membrane IDA
IDA: 通过直接分析推断
15485775 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

leucine-rich repeat transmembrane protein FLRT3

fibronectin-like domain-containing leucine-rich transmembrane protein 3

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Flrt3 NCBI NCBI:23767