2. Gene
  3. Atp2b4 - ATPase, Ca++ transporting, plasma membrane 4 Gene

Atp2b4 - ATPase, Ca++ transporting, plasma membrane 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Pmca4

基因 ID: 381290 | 基因类型: protein coding

关于 Atp2b4

功能概要

Enables scaffold protein binding activity and Sodium Channel regulator activity. Involved in several processes, including negative regulation of blood vessel endothelial cell migration; negative regulation of calcineurin-NFAT signaling cascade; and negative regulation of cardiac muscle hypertrophy in response to stress. Located in T-tubule and sperm flagellum. Part of protein-containing complex. Is expressed in several structures, including bladder; heart; intestine wall; liver; and nervous system. Orthologous to human ATP2B4 (ATPase plasma membrane Ca2+ transporting 4). [provided by Alliance of Genome Resources, Apr 2022]

Atp2b4 基因产物(2)

mRNA Protein Name
NM_001167949.2 NP_001161421.1 plasma membrane calcium-transporting ATPase 4 isoform a
NM_213616.4 NP_998781.1 plasma membrane calcium-transporting ATPase 4 isoform b
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
28827723 MGI
enables scaffold protein binding IPI
IPI: 通过物理相互作用推断
18591664 MGI
enables sodium channel regulator activity IMP
IMP: 通过突变表型推断
18591664 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to acetylcholine IMP
IMP: 通过突变表型推断
16956963 MGI
involved in flagellated sperm motility IMP
IMP: 通过突变表型推断
15078889 MGI
involved in intracellular calcium ion homeostasis IMP
IMP: 通过突变表型推断
15078889 MGI
involved in negative regulation of angiogenesis IMP
IMP: 通过突变表型推断
25147342 MGI
involved in negative regulation of blood vessel endothelial cell migration IMP
IMP: 通过突变表型推断
25147342 MGI
involved in negative regulation of calcineurin-NFAT signaling cascade IMP
IMP: 通过突变表型推断
25147342 MGI
involved in negative regulation of cardiac muscle hypertrophy in response to stress IMP
IMP: 通过突变表型推断
19287093 MGI
involved in negative regulation of gene expression IMP
IMP: 通过突变表型推断
25147342 MGI
involved in urinary bladder smooth muscle contraction IMP
IMP: 通过突变表型推断
16956963 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in T-tubule IDA
IDA: 通过直接分析推断
19287093 MGI
part of protein-containing complex IDA
IDA: 通过直接分析推断
18591664 MGI
located in sarcolemma IDA
IDA: 通过直接分析推断
19287093 MGI
located in sperm flagellum IDA
IDA: 通过直接分析推断
15078889 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

plasma membrane calcium-transporting ATPase 4

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01197 ATP2B4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20525 Atp2b4 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27034 Atp2b4 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Atp2b4 NCBI NCBI:493
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