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  2. Lpar5 - lysophosphatidic acid receptor 5 Gene

Lpar5 - lysophosphatidic acid receptor 5 Gene

中文名称:溶血磷脂酸受体 5

种属: Mus musculus

同用名: LPA5; GPR93; Gpr92; Gm1072

基因 ID: 381810 | 基因类型: protein coding

关于 Lpar5

Chromosome 6: 125,044,883-125,059,435 forward strand.GRCm39:CM000999.3

This gene has 2 transcripts (splice variants), 252 orthologues, 1 paralogue and is associated with 11 phenotypes. Biased expression in small intestine adult (RPKM 19.8), duodenum adult (RPKM 18.6) and 7 other tissues.

功能概要

预计该基因编码的蛋白可启动 G 蛋白偶联受体活性。在对疼痛的行为反应和 CREB 转录因子活性的正调节的上游或内部起作用。预测位于质膜中。预计是膜的组成部分。以多种结构表达,包括未来的大脑;直觉;免疫系统;肝;和神经系统。与人类 LPAR5(溶血磷脂酸受体 5)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable G protein-coupled receptor activity. Acts upstream of or within behavioral response to pain and positive regulation of CREB transcription factor activity. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Is expressed in several structures, including future brain; gut; immune system; liver; and nervous system. Orthologous to human LPAR5 (lysophosphatidic acid receptor 5). [provided by Alliance of Genome Resources, Apr 2022]

Lpar5 基因产物(2)

mRNA Protein Name
NM_001163269.2 NP_001156741.2 lysophosphatidic acid receptor 5
NM_001163268.2 NP_001156740.2 lysophosphatidic acid receptor 5
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within behavioral response to pain IMP
IMP: 通过突变表型推断
22461625 MGI
acts upstream of or within positive regulation of CREB transcription factor activity IMP
IMP: 通过突变表型推断
22461625 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Lpar5 蛋白结构

7tm_GPCRs

7tm_GPCRs: cl28897 (26 - 311)

7tm_GPCRs

7tm_GPCRs: cd14964 (28 - 52)

7tm_GPCRs

7tm_GPCRs: cd14964 (61 - 82)

7tm_GPCRs

7tm_GPCRs: cd14964 (98 - 120)

7tm_GPCRs

7tm_GPCRs: cd14964 (143 - 159)

7tm_GPCRs

7tm_GPCRs: cd14964 (192 - 215)

7tm_GPCRs

7tm_GPCRs: cd14964 (236 - 258)

7tm_GPCRs

7tm_GPCRs: cd14964 (279 - 304)

  • 0
  • 100
  • 200
  • 300
  • 372 a.a.
蛋白主名 其他名称

lysophosphatidic acid receptor 5

G protein-coupled receptor 92

LPA receptor 5

LPA-5

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lpar5 NCBI NCBI:57121