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  2. NANOGP8 - Nanog homeobox retrogene P8 Gene

NANOGP8 - Nanog homeobox retrogene P8 Gene

中文名称:Nanog 同源框逆转录基因 P8

种属: Homo sapiens

同用名: PN8; NANOGP1

基因 ID: 388112 | 基因类型: protein coding

关于 NANOGP8

This gene has 2 transcripts (splice variants), 233 orthologues and 9 paralogues.

功能概要

该基因代表 Nanog 同源盒基因的转录逆转录基因。推定的编码蛋白可能参与癌细胞的重编程。使用重组蛋白的体外研究表明,该蛋白定位于细胞核并可促进细胞增殖,类似于 Nanog 蛋白。[RefSeq 提供,2017 年 9 月]

This gene represents a transcribed retrogene of the Nanog homeobox gene. The putative encoded protein may participate in reprogramming of Cancer cells. In vitro studies using a recombinant protein have shown that the protein localizes to the nucleus and can promote cell proliferation, similar to the Nanog protein. [provided by RefSeq, Sep 2017]

NANOGP8 基因产物(1)

mRNA Protein Name
NM_001355281.2 NP_001342210.1 homeobox protein NANOGP8
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of cell cycle G1/S phase transition IDA
IDA: 通过直接分析推断
16623708 GOA
involved in positive regulation of cell population proliferation IDA
IDA: 通过直接分析推断
16623708 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
16623708 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

homeobox protein NANOGP8

putative homeobox protein NANOGP8

关联疾病

疾病名称 别名
Sickle Cell Anemia

Hemoglobin Sc Disease

Anemia, Sickle Cell

Hbsc Disease

Sickle Cell-Hemoglobin C Disease Syndrome

Hb Ss Disease

Sickle Cell Trait

Drepanocytosis

Haemoglobin Sc Disease

Hb Sc Disease

Hb-S/Hb-C Disease

Hb-Ss Disease Without Crisis

Hemoglobin S Disease Without Crisis

Sickle Cell Anaemia

Sickle-Cell/Hb-C Disease Without Crisis

Sickle Cell - Hemoglobin C Disease

Hbs Disease

Hemoglobin S Disease

Sickling Disorder Due To Hemoglobin S

SKCA

Sickle Cell Disease

Sickle Cell-Hemoglobin C Disease

Sickle-Cell Disease Carrier

Sickle-Cell Heterozygous Disorder

Haemoglobin A-S Genotype

Hb-S - [Sickle Cell Haemoglobin] Carrier

Sickle Cell Haemoglobin Trait

As - [Sickle Cell Trait]

Hbas - [Sickle Cell Haemoglobin Trait]

Sickle-Cell Trait Haemoglobin Disease

Haemoglobin Sickle Cell Trait Disorder

Heterozygous Sickle Cell Trait

Hbas - [Heterozygous Haemoglobin S]

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus NANOGP8 MGD MGI:1919200