1. Gene
  2. Tpm2 - tropomyosin 2 Gene

Tpm2 - tropomyosin 2 Gene

种属: Rattus norvegicus

基因 ID: 500450 | 基因类型: protein coding

关于 Tpm2

功能概要

Enables actin filament binding activity; protein heterodimerization activity; and protein homodimerization activity. Predicted to be involved in actin filament organization; muscle contraction; and regulation of ATPase activity. Located in actin Cytoskeleton. Human ortholog(s) of this gene implicated in distal arthrogryposis type 1A and nemaline myopathy 4. Orthologous to human TPM2 (tropomyosin 2). [provided by Alliance of Genome Resources, Apr 2022]

Tpm2 基因产物(2)

mRNA Protein Name
NM_001024345.2 NP_001019516.1 tropomyosin beta chain isoform Tpm2.1sm/cy
NM_001301235.1 NP_001288164.1 tropomyosin beta chain isoform Tpm2.2st
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables actin filament binding IDA
IDA: 通过直接分析推断
7568216 RGD
enables identical protein binding IDA
IDA: 通过直接分析推断
7568216 RGD
enables protein heterodimerization activity IDA
IDA: 通过直接分析推断
7568216 RGD
enables protein homodimerization activity IDA
IDA: 通过直接分析推断
7568216 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in actin cytoskeleton IDA
IDA: 通过直接分析推断
7568216 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

tropomyosin beta chain

beta-tropomyosin

tropomyosin 2, beta

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tpm2 NCBI NCBI:7169