1. Gene
  2. Sall2 - spalt like transcription factor 2 Gene

Sall2 - spalt like transcription factor 2 Gene

种属: Mus musculus

同用名: Sal-2; Msal-2; mKIAA0360; p150(Sal2)

基因 ID: 50524 | 基因类型: protein coding

关于 Sall2

功能概要

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within neural tube development. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; metanephros; neural ectoderm; reproductive system; and sensory organ. Human ortholog(s) of this gene implicated in coloboma. Orthologous to human SALL2 (spalt like transcription factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Sall2 基因产物(2)

mRNA Protein Name
NM_001244916.1 NP_001231845.1 sal-like protein 2 isoform 2
NM_015772.3 NP_056587.2 sal-like protein 2 isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein-containing complex binding IPI
IPI: 通过物理相互作用推断
16707490 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
16707490 MGI
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
16707490 MGI
acts upstream of or within neural tube development IMP
IMP: 通过突变表型推断
18818376 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

sal-like protein 2

sal-like 2

spalt-like protein 2

zinc finger protein Spalt-2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sall2 NCBI NCBI:6297