2. Gene
  3. Grem1 - gremlin 1, DAN family BMP antagonist Gene

Grem1 - gremlin 1, DAN family BMP antagonist Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: drm; Cktsf1b1

基因 ID: 50566 | 基因类型: protein coding

关于 Grem1

功能概要

Predicted to enable several functions, including BMP binding activity; protein homodimerization activity; and signaling receptor activator activity. Involved in several processes, including negative regulation of cell growth; negative regulation of monocyte chemotaxis; and positive regulation of angiogenesis. Acts upstream of or within negative regulation of osteoblast differentiation. Located in cell surface and extracellular space. Orthologous to human GREM1 (gremlin 1, Dan family BMP antagonist). [provided by Alliance of Genome Resources, Apr 2022]

Grem1 基因产物(1)

mRNA Protein Name
NM_019282.3 NP_062155.1 gremlin-1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
10722723 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of cell growth IMP
IMP: 通过突变表型推断
9234736 RGD
involved in negative regulation of leukocyte chemotaxis IDA
IDA: 通过直接分析推断
15528323 RGD
involved in negative regulation of monocyte chemotaxis IDA
IDA: 通过直接分析推断
15528323 RGD
acts upstream of or within negative regulation of osteoblast differentiation IMP
IMP: 通过突变表型推断
27910957 RGD
involved in positive regulation of angiogenesis IMP
IMP: 通过突变表型推断
17077323 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
10722723 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
10722723 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

gremlin-1

cysteine knot superfamily 1, BMP antagonist 1

down-regulated in Mos-transformed cells protein

gremlin 1 homolog, cysteine knot superfamily

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-112056 DIM-C-pPhCO2Me 99.47% 否
HY-RS05784 GREM1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17341 Grem1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23796 Grem1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P990426 Anti-GREM1/Gremlin Antibody 98.59% 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Grem1 NCBI NCBI:26585
Mus musculus Grem1 NCBI NCBI:23892
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z