2. Gene
  3. Slc6a8 - solute carrier family 6 member 8 Gene

Slc6a8 - solute carrier family 6 member 8 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: CRT; CT1; CHT1; CHOT1

基因 ID: 50690 | 基因类型: protein coding

关于 Slc6a8

功能概要

Enables choline transmembrane transporter activity and creatine:sodium symporter activity. Involved in creatine transmembrane transport and embryonic brain development. Is active in glutamatergic synapse. Is integral component of postsynaptic membrane. Biomarker of status epilepticus. Human ortholog(s) of this gene implicated in creatine transporter deficiency and intellectual disability. Orthologous to human SLC6A8 (solute carrier family 6 member 8). [provided by Alliance of Genome Resources, Apr 2022]

Slc6a8 基因产物(1)

mRNA Protein Name
NM_017348.3 NP_059044.1 sodium- and chloride-dependent creatine transporter 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables choline transmembrane transporter activity IDA
IDA: 通过直接分析推断
1633856 RGD
enables creatine transmembrane transporter activity IDA
IDA: 通过直接分析推断
8297374 RGD
enables creatine:sodium symporter activity IDA
IDA: 通过直接分析推断
8297374 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in creatine transmembrane transport IDA
IDA: 通过直接分析推断
8297374 RGD
involved in embryonic brain development IEP
IEP: 通过表达模式推断
15918910 RGD
involved in protein catabolic process EXP
EXP: 通过实验结果推断
20731764 RGD
involved in protein catabolic process IDA
IDA: 通过直接分析推断
20731764 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
12433955 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
20731764 RGD
located in plasma membrane IDA
IDA: 通过直接分析推断
32115505 RGD
is active in postsynaptic membrane IDA
IDA: 通过直接分析推断
20731764 RGD
is active in synapse EXP
EXP: 通过实验结果推断
20731764 RGD
is active in synapse IDA
IDA: 通过直接分析推断
20731764 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

sodium- and chloride-dependent creatine transporter 1

choline transporter

creatine transporter 1

solute carrier family 6 (neurotransmitter transporter), member 8

solute carrier family 6 (neurotransmitter transporter, creatine), member 8

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-W015828 Ompenaclid Inducer 99.94% Phase 2
Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-169294 SLC6A8 corrector 1 Inhibitor / 否
HY-RS13319 SLC6A8 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-169295 RAP 1 / 否
HY-181753 INSP-0154 / 否
HY-RS17671 Slc6a8 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24132 Slc6a8 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Slc6a8 NCBI NCBI:6535
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