2. Gene
  3. Dlc1 - deleted in liver cancer 1 Gene

Dlc1 - deleted in liver cancer 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: HP; dlc-1; Arhgap7; STARD12; A730069N07Rik

基因 ID: 50768 | 基因类型: protein coding

关于 Dlc1

功能概要

Predicted to enable several functions, including GTPase activator activity; SH2 domain binding activity; and Phospholipase binding activity. Acts upstream of or within several processes, including actin Cytoskeleton organization; focal adhesion assembly; and nervous system development. Predicted to be located in several cellular components, including caveola; cortical actin cytoskeleton; and ruffle membrane. Predicted to be active in focal adhesion and membrane raft. Predicted to colocalize with actin filament and stress fiber. Is expressed in several structures, including central nervous system; liver; mandible; placenta; and trigeminal nerve. Human ortholog(s) of this gene implicated in colorectal Cancer. Orthologous to human DLC1 (DLC1 Rho GTPase activating protein). [provided by Alliance of Genome Resources, Apr 2022]

Dlc1 基因产物(3)

mRNA Protein Name
NM_001194940.2 NP_001181869.1 rho GTPase-activating protein 7 isoform 1
NM_001194941.1 NP_001181870.1 rho GTPase-activating protein 7 isoform 3
NM_015802.3 NP_056617.2 rho GTPase-activating protein 7 isoform 2
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within actin cytoskeleton organization IMP
IMP: 通过突变表型推断
15710412 MGI
acts upstream of or within focal adhesion assembly IMP
IMP: 通过突变表型推断
15710412 MGI
acts upstream of or within forebrain development IMP
IMP: 通过突变表型推断
15710412 MGI
acts upstream of or within heart morphogenesis IMP
IMP: 通过突变表型推断
15710412 MGI
acts upstream of or within hindbrain morphogenesis IMP
IMP: 通过突变表型推断
15710412 MGI
acts upstream of or within neural tube closure IMP
IMP: 通过突变表型推断
15710412 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

rho GTPase-activating protein 7

START domain-containing protein 12

p122-RhoGAP

rho-type GTPase-activating protein 7

stAR-related lipid transfer protein 12

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03793 DLC1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS03795 DLEC1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS04088 DYNLL1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19126 Dlc1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25616 Dlc1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dlc1 NCBI NCBI:10395
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