Dmrt1 - doublesex and mab-3 related transcription factor 1 Gene

种属: Mus musculus

关于 Dmrt1

功能概要

Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; identical protein binding activity; and transcription cis-regulatory region binding activity. Involved in several processes, including male germ cell proliferation; regulation of nuclear division; and regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including gamete generation; positive regulation of male gonad development; and positive regulation of meiosis I. Located in cytoplasm and nucleus. Is expressed in several structures, including early conceptus; gonad; gonad primordium; and mesonephros. Orthologous to human DMRT1 (doublesex and mab-3 related transcription factor 1). [provided by Alliance of Genome Resources, Apr 2022]