2. Gene
  3. PLAC8 - placenta associated 8 Gene

PLAC8 - placenta associated 8 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：胎盘相关 8

种属: Homo sapiens

同用名: C15; DGIC; onzin; PNAS-144

基因 ID: 51316 | 基因类型: protein coding

关于 PLAC8

Cytogenetic location: 4q21.22 Genomic coordinates (GRCh38): 4:83,090,048-83,114,729 (from NCBI)

This gene has 6 transcripts (splice variants), 220 orthologues and 2 paralogues. Biased expression in bone marrow (RPKM 48.1), colon (RPKM 47.5) and 10 other tissues.

功能概要

预测启用染色质结合活性。预计参与冷诱导产热的正调节和 RNA 聚合酶 II 转录的正调节。预计在几个过程的上游或内部起作用，包括棕色脂肪细胞分化；对细菌的防御反应；和对寒冷的反应。预测位于嗜苯胺青颗粒腔和胞外区。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable chromatin binding activity. Predicted to be involved in positive regulation of cold-induced thermogenesis and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including brown fat cell differentiation; defense response to bacterium; and response to cold. Predicted to be located in azurophil granule lumen and extracellular region. [provided by Alliance of Genome Resources, Apr 2022]

PLAC8 基因产物(3)

mRNA Protein Name
NM_001130715.2 NP_001124187.1 placenta-specific gene 8 protein
NM_001130716.2 NP_001124188.1 placenta-specific gene 8 protein
NM_016619.3 NP_057703.1 placenta-specific gene 8 protein

PLAC8 蛋白结构

PLAC8

PLAC8: PLAC8 family (26 - 105)

  • 0
  • 100
  • 115 a.a.
蛋白主名 其他名称

placenta-specific gene 8 protein

down-regulated in gastrointestinal cancer protein

关联疾病

疾病名称 别名
Hypoglycemia, Leucine-Induced

Leucine-Sensitive Hypoglycemia Of Infancy

Leucine-Induced Hypoglycemia

LIH

Hypoglycemia Of Infancy, Leucine-Sensitive

Familial Infantile Hypoglycemia Precipitated By Leucine

Hypoglycemia Leucine Induced

Hypoglycemia Leucine-Induced
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10641 PLAC8 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19731 Plac8 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26227 Plac8 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus PLAC8 VGNC VGNC:56782
Mus musculus PLAC8 MGD MGI:2445289
Rattus norvegicus PLAC8 RGD RGD:1308102
Canis familiaris PLAC8 VGNC VGNC:44636
Macaca mulatta PLAC8 VGNC VGNC:76072
Felis catus PLAC8 VGNC VGNC:79364
Others PLAC8 NCBI
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