2. Gene
  3. Map3k14 - mitogen-activated protein kinase kinase kinase 14 Gene

Map3k14 - mitogen-activated protein kinase kinase kinase 14 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Nik; aly

基因 ID: 53859 | 基因类型: protein coding

关于 Map3k14

功能概要

Enables NF-kappaB-inducing kinase activity. Involved in I-kappaB kinase/NF-kappaB signaling and immune response. Predicted to be located in cytosol; fibrillar center; and nucleoplasm. Is expressed in several structures, including alimentary system; cardiovascular system; nervous system; sensory organ; and skeleton. Used to study Sjogren's syndrome and primary biliary cholangitis. Orthologous to human MAP3K14 (mitogen-activated protein kinase kinase kinase 14). [provided by Alliance of Genome Resources, Apr 2022]

Map3k14 基因产物(1)

mRNA Protein Name
NM_016896.3 NP_058592.1 mitogen-activated protein kinase kinase kinase 14
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
11239468 MGI
enables protein serine/threonine kinase activity IDA
IDA: 通过直接分析推断
11239468 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in immune response IDA
IDA: 通过直接分析推断
11239468 MGI
involved in non-canonical NF-kappaB signal transduction IDA
IDA: 通过直接分析推断
11239468 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

mitogen-activated protein kinase kinase kinase 14

NF kappa B-inducing kinase

NF-kappa-beta-inducing kinase

Nfkb inducing kinase

alymphoplasia

serine/threonine-protein kinase NIK

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08051 MAP3K14 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20213 Map3k14 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26718 Map3k14 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Map3k14 NCBI NCBI:9020
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