2. Gene
  3. Eif2ak2 - eukaryotic translation initiation factor 2-alpha kinase 2 Gene

Eif2ak2 - eukaryotic translation initiation factor 2-alpha kinase 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Pkr; Prkr

基因 ID: 54287 | 基因类型: protein coding

关于 Eif2ak2

功能概要

Predicted to enable double-stranded RNA binding activity; eukaryotic translation initiation factor 2alpha kinase activity; and identical protein binding activity. Involved in several processes, including response to exogenous dsRNA; response to lipopolysaccharide; and response to vitamin E. Located in nucleus. Biomarker of pulmonary venoocclusive disease. Human ortholog(s) of this gene implicated in Alzheimer's disease; Huntington's disease; Parkinson's disease; and hepatitis B. Orthologous to human EIF2AK2 (eukaryotic translation initiation factor 2 alpha kinase 2). [provided by Alliance of Genome Resources, Apr 2022]

Eif2ak2 基因产物(1)

mRNA Protein Name
NM_019335.2 NP_062208.2 interferon-induced, double-stranded RNA-activated protein kinase
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
17953670 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of apoptotic process IMP
IMP: 通过突变表型推断
18535002 RGD
involved in response to exogenous dsRNA IEP
IEP: 通过表达模式推断
15920723 RGD
involved in response to lipopolysaccharide IMP
IMP: 通过突变表型推断
15630703 RGD
involved in response to mechanical stimulus IEP
IEP: 通过表达模式推断
15781241 RGD
involved in response to toxic substance IMP
IMP: 通过突变表型推断
18535002 RGD
involved in response to vitamin E IPI
IPI: 通过物理相互作用推断
17953670 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

interferon-induced, double-stranded RNA-activated protein kinase

Protein kinase, interferon-inducible double stranded RNA dependent

eIF-2A protein kinase 2

interferon-inducible RNA-dependent protein kinase

protein kinase R

protein kinase RNA-activated

tyrosine-protein kinase EIF2AK2

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04243 EIF2AK2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-174720 Human EIF2AK2 mRNA / 否
HY-RS18207 Eif2ak2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24684 Eif2ak2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Eif2ak2 NCBI NCBI:5610
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