2. Gene
  3. Ncor1 - nuclear receptor co-repressor 1 Gene

Ncor1 - nuclear receptor co-repressor 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Rxrip13

基因 ID: 54299 | 基因类型: protein coding

关于 Ncor1

功能概要

Enables several functions, including RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; nuclear receptor binding activity; and peroxisome proliferator activated receptor binding activity. Involved in animal organ development; negative regulation of macromolecule metabolic process; and positive regulation of cell population proliferation. Located in nucleus and perinuclear region of cytoplasm. Used to study anxiety disorder and polycystic ovary syndrome. Biomarker of hypothyroidism and polycystic ovary syndrome. Orthologous to human NCOR1 (nuclear receptor corepressor 1). [provided by Alliance of Genome Resources, Apr 2022]

Ncor1 基因产物(1)

mRNA Protein Name
NM_001271103.1 NP_001258032.1 nuclear receptor corepressor 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
17079677 RGD
enables chromatin binding IDA
IDA: 通过直接分析推断
20352046 RGD
enables histone deacetylase binding IPI
IPI: 通过物理相互作用推断
17079677 RGD
enables nuclear estrogen receptor binding IPI
IPI: 通过物理相互作用推断
19460436 RGD
enables nuclear retinoic acid receptor binding IPI
IPI: 通过物理相互作用推断
15234273 RGD
enables nuclear retinoid X receptor binding IPI
IPI: 通过物理相互作用推断
15234273 RGD
enables peroxisome proliferator activated receptor binding IPI
IPI: 通过物理相互作用推断
15870285 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
10441327 RGD
enables protein domain specific binding IPI
IPI: 通过物理相互作用推断
10441327 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cerebellum development IEP
IEP: 通过表达模式推断
10803578 RGD
involved in lactation IEP
IEP: 通过表达模式推断
15946693 RGD
involved in negative regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
9139820 RGD
involved in negative regulation of gene expression IMP
IMP: 通过突变表型推断
19608741 RGD
involved in positive regulation of cell population proliferation IMP
IMP: 通过突变表型推断
19608741 RGD
involved in skeletal muscle tissue development IEP
IEP: 通过表达模式推断
9839950 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
19696011 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

nuclear receptor corepressor 1

N-CoR

N-CoR1

N-Cor/SMRT corepressor, Rip13

NCoR

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-121900 LT175 Agonist 99.79% 否
HY-176851 GSK1362 Inhibitor 96.38% 否
HY-177756 BCL6-IN-11 Inhibitor / 否
HY-RS09096 NCOR1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20452 Ncor1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26961 Ncor1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ncor1 NCBI NCBI:9611
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z