DNAH3 - dynein axonemal heavy chain 3 Gene

中文名称：动力蛋白轴丝重链 3

种属: Homo sapiens

同用名: HDHC8; HEL-36; DNAHC3B; HSADHC3; DNAHC3-B

关于 DNAH3

功能概要

该基因属于动力蛋白家族，其成员编码大蛋白，这些大蛋白是微管相关运动蛋白复合物的组成部分。该复合物由动力蛋白重链、中间链和轻链组成，可以是轴丝或细胞质的。这种蛋白质是轴丝动力蛋白重链。它通过使用来自 ATP 水解的能量参与产生纤毛跳动的力量。可变剪接导致编码不同异构体的多个转录变体。[RefSeq 提供，2016 年 12 月]

This gene belongs to the dynein family, whose members encode large proteins that are constituents of the microtubule-associated motor protein complex. This complex is composed of dynein heavy, intermediate and light chains, which can be axonemal or cytoplasmic. This protein is an axonemal dynein heavy chain. It is involved in producing force for ciliary beating by using energy from ATP hydrolysis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Dec 2016]