2. Gene
  3. ZNF395 - zinc finger protein 395 Gene

ZNF395 - zinc finger protein 395 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：锌指蛋白 395

种属: Homo sapiens

同用名: PBF; PRF1; HDBP2; PRF-1; HDBP-2; HDRF-2; Si-1-8-14

基因 ID: 55893 | 基因类型: protein coding

关于 ZNF395

Cytogenetic location: 8p21.1 Genomic coordinates (GRCh38): 8:28,345,590-28,386,460 (from NCBI)

This gene has 11 transcripts (splice variants), 257 orthologues and 2 paralogues. Ubiquitous expression in ovary (RPKM 29.1), placenta (RPKM 20.8) and 25 other tissues.

功能概要

启用 DNA 结合转录激活因子活性、RNA 聚合酶 II 特异性和 RNA 聚合酶 II 顺式调节区序列特异性 DNA 结合活性。参与 RNA 聚合酶 II 对转录的正调控。位于胞质溶胶和核斑点。 [由基因组资源联盟提供，2022 年 4 月]

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Located in cytosol and nuclear speck. [provided by Alliance of Genome Resources, Apr 2022]

ZNF395 基因产物(1)

mRNA Protein Name
NM_018660.3 NP_061130.1 zinc finger protein 395
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
14625278 GOA
enables DNA-binding transcription activator activity, RNA polymerase II-specific IMP
IMP: 通过突变表型推断
28316371 GOA
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
14625278 GOA
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IMP
IMP: 通过突变表型推断
14625278 GOA
enables cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
11853404 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
17531190 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
28316371 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
14625278 GOA
located in nucleus IDA
IDA: 通过直接分析推断
14625278 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

zinc finger protein 395

HD gene regulatory region-binding protein 2

关联疾病

疾病名称 别名
Huntington Disease

Huntington'S Disease

Huntington Chorea

Huntington'S Chorea

HD

Huntington Chronic Progressive Hereditary Chorea

Juvenile Huntington Disease

Chronic Progressive Chorea

Chronic Progressive Hereditary Chorea

Hc - [Huntington Chorea]

Hereditary Chorea

Progressive Hereditary Chorea
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS16136 ZNF395 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris ZNF395 VGNC VGNC:48717
Bos taurus ZNF395 VGNC VGNC:37266
Macaca mulatta ZNF395 VGNC VGNC:104508
Mus musculus ZNF395 MGD MGI:2682318
Rattus norvegicus ZNF395 RGD RGD:1307849
Felis catus ZNF395 VGNC VGNC:67304
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