2. Gene
  3. BEX4 - brain expressed X-linked 4 Gene

BEX4 - brain expressed X-linked 4 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：脑表达 X 连锁 4

种属: Homo sapiens

同用名: BEXL1

基因 ID: 56271 | 基因类型: protein coding

关于 BEX4

Cytogenetic location: Xq22.1 Genomic coordinates (GRCh38): X:103,215,092-103,217,246 (from NCBI)

This gene has 2 transcripts (splice variants) and 80 orthologues. Ubiquitous expression in brain (RPKM 111.7), thyroid (RPKM 67.9) and 23 other tissues.

功能概要

该基因是脑表达 X 连锁基因家族的成员。由该家族的一些其他成员编码的蛋白质充当转录延伸因子，使 RNA 聚合酶 II 在延伸过程中避免暂停。已经鉴定出编码相同蛋白质的多个可变剪接变体。[RefSeq 提供，2011 年 8 月]

This gene is a member of the brain expressed X-linked gene family. The proteins encoded by some of the Other members of this family act as transcription elongation factors which allow RNA polymerase II to escape pausing during elongation. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Aug 2011]

BEX4 基因产物(2)

mRNA Protein Name
NM_001080425.4 NP_001073894.1 protein BEX4
NM_001127688.2 NP_001121160.1 protein BEX4
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables alpha-tubulin binding IDA
IDA: 通过直接分析推断
27512957 GOA
enables histone deacetylase binding IPI
IPI: 通过物理相互作用推断
27512957 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in chromosome segregation IMP
IMP: 通过突变表型推断
27512957 GOA
involved in negative regulation of tubulin deacetylation IMP
IMP: 通过突变表型推断
27512957 GOA
involved in regulation of cell migration IMP
IMP: 通过突变表型推断
27512957 GOA
involved in regulation of cell population proliferation IMP
IMP: 通过突变表型推断
27512957 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
27512957 GOA
located in microtubule IDA
IDA: 通过直接分析推断
27512957 GOA
located in nucleus IDA
IDA: 通过直接分析推断
27512957 GOA
located in spindle pole IDA
IDA: 通过直接分析推断
27512957 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

BEX4 蛋白结构

BEX

BEX: Brain expressed X-linked like family (15 - 119)

  • 0
  • 100
  • 120 a.a.
蛋白主名 其他名称

protein BEX4

BEX family member 4

关联疾病

疾病名称 别名
Hypoglycemia, Leucine-Induced

Leucine-Sensitive Hypoglycemia Of Infancy

Leucine-Induced Hypoglycemia

LIH

Hypoglycemia Of Infancy, Leucine-Sensitive

Familial Infantile Hypoglycemia Precipitated By Leucine

Hypoglycemia Leucine Induced

Hypoglycemia Leucine-Induced
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01483 BEX4 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus BEX4 MGD MGI:3606746
Rattus norvegicus BEX4 RGD RGD:1564749
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z