2. Gene
  3. Spen - spen family transcription repressor Gene

Spen - spen family transcription repressor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Mint; mKIAA0929

基因 ID: 56381 | 基因类型: protein coding

关于 Spen

功能概要

Enables DNA-binding transcription factor activity; single-stranded DNA binding activity; and transcription corepressor activity. Acts upstream of or within negative regulation of transcription, DNA-templated and positive regulation of transcription, DNA-templated. Located in nucleus. Is expressed in central nervous system; genitourinary system; hemolymphoid system; sensory organ; and tooth. Orthologous to human SPEN (spen family transcriptional repressor). [provided by Alliance of Genome Resources, Apr 2022]

Spen 基因产物(2)

mRNA Protein Name
NM_001347235.1 NP_001334164.1 msx2-interacting protein isoform 2
NM_019763.2 NP_062737.2 msx2-interacting protein isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
NOT enables DNA binding IDA
IDA: 通过直接分析推断
15778499 MGI
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
10451362 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
10451362 MGI
enables single-stranded DNA binding IDA
IDA: 通过直接分析推断
10451362 MGI
enables transcription corepressor activity IDA
IDA: 通过直接分析推断
15778499 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
10451362 MGI
acts upstream of or within positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
10451362 MGI
involved in random inactivation of X chromosome IMP
IMP: 通过突变表型推断
25915022 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
10451362 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

msx2-interacting protein

Msx2 interacting nuclear target protein

SMART/HDAC1-associated repressor protein

SPEN homolog, transcriptional regulator

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-152038 SPEN-IN-1 97.25% 否
HY-RS11735 RBM15 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS13660 SPEN Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20339 Spen Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26847 Spen Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Spen NCBI NCBI:23013
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z