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  3. Clec4e - C-type lectin domain family 4, member e Gene

Clec4e - C-type lectin domain family 4, member e Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Mincle; Clecsf9

基因 ID: 56619 | 基因类型: protein coding

关于 Clec4e

功能概要

Enables glycolipid binding activity and pattern recognition receptor activity. Involved in Antifungal innate immune response and positive regulation of cytokine production. Acts upstream of or within Fc-gamma Receptor signaling pathway; T cell differentiation involved in immune response; and defense response to bacterium. Is active in phagocytic vesicle membrane and plasma membrane. Orthologous to human CLEC4E (C-type lectin domain family 4 member E). [provided by Alliance of Genome Resources, Apr 2022]

Clec4e 基因产物(1)

mRNA Protein Name
NM_019948.2 NP_064332.1 C-type lectin domain family 4 member E
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables glycolipid binding IPI
IPI: 通过物理相互作用推断
20008526 MGI
enables pattern recognition receptor activity IDA
IDA: 通过直接分析推断
20008526 MGI
enables pattern recognition receptor activity IMP
IMP: 通过突变表型推断
18490740 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
18776906 MGI
enables signaling receptor activity IDA
IDA: 通过直接分析推断
18776906 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within Fc-gamma receptor signaling pathway IDA
IDA: 通过直接分析推断
23602766 MGI
acts upstream of or within T cell differentiation involved in immune response IMP
IMP: 通过突变表型推断
23602766 MGI
involved in antifungal innate immune response IMP
IMP: 通过突变表型推断
18490740 MGI
acts upstream of or within defense response to bacterium IMP
IMP: 通过突变表型推断
23602766 MGI
involved in immune response IMP
IMP: 通过突变表型推断
19171887 MGI
involved in innate immune response IDA
IDA: 通过直接分析推断
20008526 MGI
acts upstream of or within innate immune response IMP
IMP: 通过突变表型推断
23602766 MGI
involved in positive regulation of cytokine production IDA
IDA: 通过直接分析推断
18776906 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in phagocytic vesicle membrane IDA
IDA: 通过直接分析推断
18490740 MGI
is active in plasma membrane IDA
IDA: 通过直接分析推断
18490740 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

C-type lectin domain family 4 member E

C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 9

C-type lectin, superfamily member 9

macrophage-inducible C-type lectin

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02794 CLEC4E Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17848 Clec4e Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24316 Clec4e Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Clec4e NCBI NCBI:26253
Macaca mulatta Clec4e NCBI NCBI:722250
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