PANX2 - pannexin 2 Gene

中文名称：泛联蛋白 2

种属: Homo sapiens

同用名: PX2; hPANX2

关于 PANX2

功能概要

该基因编码的蛋白质属于内联蛋白家族。 Innexin 家族成员是间隙连接的结构成分。这种蛋白质和 pannexin 1 在中枢神经系统 (CNS) 中大量表达，并在各种神经元群中共表达。对非洲爪蟾卵母细胞的研究表明，这种蛋白质单独和与 pannexin 1 结合可能形成具有不同特性的细胞类型特异性间隙连接。已发现该基因编码不同异构体的多个转录变体。[RefSeq 提供，2009 年 5 月]

The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 1 are abundantly expressed in central nervous system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 1 may form cell type-specific gap junctions with distinct properties. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]