OLFML3 - olfactomedin like 3 Gene

中文名称：嗅觉调节素样 3

种属: Homo sapiens

同用名: OLF44; HNOEL-iso

关于 OLFML3

功能概要

该基因编码嗅调蛋白样基因家族的一个成员，该家族还包括编码 noelin、tiarin、myocilin、amassin、optimedin、photomedin 和 latrophilin 的基因。编码的蛋白质是一种分泌的细胞外基质糖蛋白，具有促进蛋白质-蛋白质相互作用、细胞粘附和细胞间相互作用的 C 末端嗅觉调节素结构域。它既是一种支架蛋白，可将骨形态发生蛋白 1 募集到其底物 chordin，又是一种具有促血管生成特性的血管组织重塑剂。可变剪接导致多个转录本变体。[RefSeq 提供，2017 年 2 月]

This gene encodes a member of the olfactomedin-like gene family which also includes genes encoding noelin, tiarin, myocilin, amassin, optimedin, photomedin, and latrophilin. The encoded protein is a secreted extracellular matrix glycoprotein with a C-terminal olfactomedin domain that facilitates protein-protein interactions, cell adhesion, and intercellular interactions. It serves as both a scaffold protein that recruits bone morphogenetic protein 1 to its substrate chordin, and as a vascular tissue remodeler with pro-angiogenic properties. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]