2. Gene
  3. DISP3 - dispatched RND transporter family member 3 Gene

DISP3 - dispatched RND transporter family member 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：派遣 RND 转运蛋白家族成员 3

种属: Homo sapiens

同用名: PTCHD2

基因 ID: 57540 | 基因类型: protein coding

关于 DISP3

Cytogenetic location: 1p36.22 Genomic coordinates (GRCh38): 1:11,479,155-11,537,551 (from NCBI)

This gene has 3 transcripts (splice variants), 200 orthologues and 10 paralogues. Biased expression in brain (RPKM 1.6), testis (RPKM 1.4) and 1 other tissue.

功能概要

参与神经元分化的负调控；脂质代谢过程的正向调节；和神经前体细胞增殖的正调节。位于细胞质中。 [由基因组资源联盟提供，2022 年 4 月]

Involved in negative regulation of neuron differentiation; positive regulation of lipid metabolic process; and positive regulation of neural precursor cell proliferation. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

DISP3 基因产物(1)

mRNA Protein Name
NM_020780.2 NP_065831.1 protein dispatched homolog 3
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of neuron differentiation IDA
IDA: 通过直接分析推断
25281927 GOA
involved in positive regulation of lipid metabolic process IDA
IDA: 通过直接分析推断
25281927 GOA
involved in positive regulation of neural precursor cell proliferation IDA
IDA: 通过直接分析推断
25281927 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
25281927 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

DISP3 蛋白结构

Patched

Patched: Patched family (416 - 698)

MMPL

MMPL: MMPL family (1185 - 1347)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1392 a.a.
蛋白主名 其他名称

protein dispatched homolog 3

dispatched 3

关联疾病

疾病名称 别名
Scrotum Melanoma

Melanoma Of Scrotum
Cataract 8, Multiple Types

Ccv

Cataract, Congenital, Volkmann Type

CTRCT8

Cataract 8 Multiple Types

Cataract Congenital Volkmann Type

Cutaneous Collagenous Vasculopathy
Anus Benign Neoplasm

Anal Neoplasm

Anal Tumors

Neoplasm Of Anus

Anus Neoplasms
Actinomycosis

Actinomycetoma

Boil

Canaliculitis

Actinomycotic Infection

Actinomycotic Madura Foot

Keratoactinomycosis

Furuncle

Actinomycotic Mycetema

Actinomycotic Mycetoma Of Foot

Madura Foot Due To Actinomadura

Actinomyces Israeli

Actinomycetes

Anaerobic Actinomyces Infection

Actinomycotic Infection Of Unspecified Site

Actinomycosis Nos

Actinomycotic Node

Actinomyces Infection

Actinomycotic Mycetoma

Mycetoma Due To Filamentous Bacteria
Scrotum Neoplasm

Malignant Tumour Of Scrotum

Malignant Scrotal Neoplasm

Malignant Tumor Of Scrotum

Neoplasm Of Scrotum

Scrotal Ca

Scrotal Tumor

Scrotum Cancer

Cancer Of Scrotum

Malignant Neoplasm Of Scrotum

Scrotal Cancer

Malignant Scrotal Tumour

Malignant Neoplasm Of Skin Of Scrotum

Primary Malignant Neoplasm Of Scrotum
Zika Virus Congenital Syndrome

Zikv Congenital Infection
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03784 DISP3 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus DISP3 RGD RGD:1305820
Mus musculus DISP3 MGD MGI:2444403
Felis catus DISP3 VGNC VGNC:61504
Bos taurus DISP3 VGNC VGNC:28076
Canis familiaris DISP3 VGNC VGNC:39968
Macaca mulatta DISP3 VGNC VGNC:106348
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