1. Gene
  2. Mlxipl - MLX interacting protein-like Gene

Mlxipl - MLX interacting protein-like Gene

种属: Mus musculus

同用名: Mlx; ChREBP; WS-bHLH; Wbscr14; bHLHd14

基因 ID: 58805 | 基因类型: protein coding

关于 Mlxipl

功能概要

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Contributes to DNA binding activity. Involved in glucose mediated signaling pathway; positive regulation of fatty acid biosynthetic process; and regulation of nucleobase-containing compound metabolic process. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Part of transcription regulator complex. Is expressed in several structures, including central nervous system; gut; liver; metanephros; and nose. Used to study irritable bowel syndrome. Orthologous to human MLXIPL (MLX interacting protein like). [provided by Alliance of Genome Resources, Apr 2022]

Mlxipl 基因产物(2)

mRNA Protein Name
NM_001359237.1 NP_001346166.1 carbohydrate-responsive element-binding protein isoform 2
NM_021455.5 NP_067430.2 carbohydrate-responsive element-binding protein isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in glucose homeostasis IMP
IMP: 通过突变表型推断
15118080 MGI
involved in glucose mediated signaling pathway IDA
IDA: 通过直接分析推断
18591247 MGI
involved in negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
11230181 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
11230181 MGI
involved in positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
15163635 MGI
involved in positive regulation of fatty acid biosynthetic process IMP
IMP: 通过突变表型推断
15118080 MGI
involved in positive regulation of glycolytic process IDA
IDA: 通过直接分析推断
14742444 MGI
involved in positive regulation of glycolytic process IMP
IMP: 通过突变表型推断
15118080 MGI
involved in positive regulation of lipid biosynthetic process IGI
IGI: 通过遗传相互作用推断
21471514 MGI
involved in positive regulation of lipid biosynthetic process IMP
IMP: 通过突变表型推断
15496471 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
18606808 MGI
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
15118080 MGI
involved in positive regulation of transcription from RNA polymerase II promoter by glucose IDA
IDA: 通过直接分析推断
14742444 MGI
involved in positive regulation of transcription from RNA polymerase II promoter by glucose IGI
IGI: 通过遗传相互作用推断
21471514 MGI
involved in positive regulation of transcription from RNA polymerase II promoter by glucose IMP
IMP: 通过突变表型推断
15496471 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
15163635 MGI
is active in nucleoplasm IDA
IDA: 通过直接分析推断
18606808 MGI
is active in nucleus IDA
IDA: 通过直接分析推断
21084751 MGI
located in nucleus IDA
IDA: 通过直接分析推断
15163635 MGI
is active in nucleus IMP
IMP: 通过突变表型推断
15496471 MGI
part of transcription regulator complex IDA
IDA: 通过直接分析推断
11230181 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

carbohydrate-responsive element-binding protein

MLX interacting protein-like beta

MLX interactor

Max-like protein

Williams-Beuren syndrome chromosome region 14 homolog

putative hepatic transcription factor

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mlxipl NCBI NCBI:51085