2. Gene
  3. Dynll1 - dynein light chain LC8-type 1 Gene

Dynll1 - dynein light chain LC8-type 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Pin; Dlc8; 8kDLC; Dnclc1

基因 ID: 58945 | 基因类型: protein coding

关于 Dynll1

功能概要

Enables several functions, including identical protein binding activity; nitric-oxide synthase regulator activity; and scaffold protein binding activity. Involved in positive regulation of Insulin secretion involved in cellular response to glucose stimulus and spermatid development. Acts upstream of or within negative regulation of nitric oxide biosynthetic process. Located in axon cytoplasm; nucleus; and secretory granule. Part of cytoplasmic dynein complex. Colocalizes with mitochondrion. Used to study hypertension and impotence. Biomarker of cardiac arrest; congestive heart failure; and middle cerebral artery infarction. Orthologous to human DYNLL1 (dynein light chain LC8-type 1). [provided by Alliance of Genome Resources, Apr 2022]

Dynll1 基因产物(1)

mRNA Protein Name
NM_053319.4 NP_445771.1 dynein light chain 1, cytoplasmic
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables enzyme binding IPI
IPI: 通过物理相互作用推断
14760703 RGD
enables enzyme inhibitor activity IDA
IDA: 通过直接分析推断
8864115 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
12904292 RGD
enables nitric-oxide synthase inhibitor activity IDA
IDA: 通过直接分析推断
8864115 RGD
enables nitric-oxide synthase regulator activity IDA
IDA: 通过直接分析推断
8864115 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
15384421 RGD
enables protein-containing complex binding IDA
IDA: 通过直接分析推断
17965411 RGD
enables scaffold protein binding IPI
IPI: 通过物理相互作用推断
12097491 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of nitric oxide biosynthetic process IDA
IDA: 通过直接分析推断
8864115 RGD
involved in negative regulation of nitric oxide biosynthetic process IDA
IDA: 通过直接分析推断
8864115 RGD
involved in positive regulation of insulin secretion involved in cellular response to glucose stimulus IDA
IDA: 通过直接分析推断
17130471 RGD
involved in spermatid development IEP
IEP: 通过表达模式推断
15983119 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon cytoplasm IDA
IDA: 通过直接分析推断
19641106 RGD
part of cytoplasmic dynein complex IDA
IDA: 通过直接分析推断
8702622 RGD
located in secretory granule IDA
IDA: 通过直接分析推断
17130471 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

dynein light chain 1, cytoplasmic

8 kDa dynein light chain

8kD LC

dynein LC8

dynein, cytoplasmic, light chain 1

protein inhibitor of neuronal nitric oxide synthase

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04088 DYNLL1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19253 Dynll1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25742 Dynll1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dynll1 NCBI NCBI:8655
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