2. Gene
  3. Kmo - kynurenine 3-monooxygenase Gene

Kmo - kynurenine 3-monooxygenase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 59113 | 基因类型: protein coding

关于 Kmo

功能概要

Enables kynurenine 3-monooxygenase activity. Involved in several processes, including carboxylic acid metabolic process; cellular response to interleukin-1; and positive regulation of glutamate secretion, neurotransmission. Located in extracellular space and mitochondrial outer membrane. Used to study schizophrenia. Biomarker of mental depression. Orthologous to human KMO (kynurenine 3-monooxygenase). [provided by Alliance of Genome Resources, Apr 2022]

Kmo 基因产物(1)

mRNA Protein Name
NM_021593.2 NP_067604.1 kynurenine 3-monooxygenase
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables kynurenine 3-monooxygenase activity IDA
IDA: 通过直接分析推断
1332540 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in L-kynurenine metabolic process IDA
IDA: 通过直接分析推断
23690293 RGD
involved in NAD metabolic process IDA
IDA: 通过直接分析推断
1332540 RGD
involved in cellular response to interleukin-1 IEP
IEP: 通过表达模式推断
25675848 RGD
involved in cellular response to lipopolysaccharide IEP
IEP: 通过表达模式推断
26524415 RGD
involved in kynurenic acid biosynthetic process IMP
IMP: 通过突变表型推断
15829251 RGD
involved in kynurenine metabolic process IDA
IDA: 通过直接分析推断
26752518 RGD
involved in positive regulation of glutamate secretion IMP
IMP: 通过突变表型推断
15829251 RGD
involved in positive regulation of glutamate secretion, neurotransmission IMP
IMP: 通过突变表型推断
15829251 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
18584961 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
29217494 RGD
located in mitochondrial outer membrane IDA
IDA: 通过直接分析推断
1332540 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

kynurenine 3-monooxygenase

kynurenine 3-hydroxylase

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-12347 Ro 61-8048 Inhibitor 99.93% 否
HY-112179 GSK180 Inhibitor 98.34% 否
HY-W748591 Cannflavin A Inhibitor 99.20% 否
HY-15500 JM6 Inhibitor / 否
HY-182456 CHDI-340246 Inhibitor / 否
HY-182692 KMO-IN-1 Inhibitor / 否
HY-181988 DTB-acid / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Kmo NCBI NCBI:8564
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