2. Gene
  3. Dusp10 - dual specificity phosphatase 10 Gene

Dusp10 - dual specificity phosphatase 10 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: MKP5; MKP-5; 2610306G15Rik

基因 ID: 63953 | 基因类型: protein coding

关于 Dusp10

功能概要

Enables MAP kinase Phosphatase activity. Involved in several processes, including negative regulation of ERK1 and ERK2 cascade; negative regulation of epithelial cell migration; and negative regulation of epithelium regeneration. Acts upstream of or within several processes, including negative regulation of protein kinase activity; negative regulation of respiratory burst involved in inflammatory response; and oligodendrocyte differentiation. Predicted to be located in Golgi apparatus; cytosol; and nuclear speck. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human DUSP10 (dual specificity Phosphatase 10). [provided by Alliance of Genome Resources, Apr 2022]

Dusp10 基因产物(1)

mRNA Protein Name
NM_022019.6 NP_071302.2 dual specificity protein phosphatase 10
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables MAP kinase phosphatase activity IDA
IDA: 通过直接分析推断
25772234 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of ERK1 and ERK2 cascade IMP
IMP: 通过突变表型推断
25772234 MGI
acts upstream of or within negative regulation of JNK cascade IMP
IMP: 通过突变表型推断
15306813 MGI
acts upstream of or within negative regulation of JUN kinase activity IMP
IMP: 通过突变表型推断
15306813 MGI
involved in negative regulation of epithelial cell migration IMP
IMP: 通过突变表型推断
25772234 MGI
involved in negative regulation of epithelial cell proliferation IMP
IMP: 通过突变表型推断
25772234 MGI
involved in negative regulation of epithelium regeneration IDA
IDA: 通过直接分析推断
25772234 MGI
acts upstream of or within negative regulation of protein kinase activity by regulation of protein phosphorylation IDA
IDA: 通过直接分析推断
23977283 MGI
acts upstream of or within negative regulation of respiratory burst involved in inflammatory response IMP
IMP: 通过突变表型推断
19696743 MGI
acts upstream of or within negative regulation of stress-activated MAPK cascade IMP
IMP: 通过突变表型推断
19696743 MGI
acts upstream of or within oligodendrocyte differentiation IMP
IMP: 通过突变表型推断
19139271 MGI
involved in protein dephosphorylation IDA
IDA: 通过直接分析推断
25772234 MGI
acts upstream of or within regulation of adaptive immune response IMP
IMP: 通过突变表型推断
15306813 MGI
acts upstream of or within regulation of brown fat cell differentiation IDA
IDA: 通过直接分析推断
23874687 MGI
acts upstream of or within regulation of innate immune response IMP
IMP: 通过突变表型推断
15306813 MGI
acts upstream of or within response to lipopolysaccharide IMP
IMP: 通过突变表型推断
19696743 MGI
acts upstream of stress-activated MAPK cascade IMP
IMP: 通过突变表型推断
19696743 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

dual specificity protein phosphatase 10

MAP kinase phosphatase 5

mitogen-activated protein kinase phosphatase 5

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04051 DUSP10 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21119 Dusp10 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27638 Dusp10 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dusp10 NCBI NCBI:11221
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