2. Gene
  3. Rab5a - RAB5A, member RAS oncogene family Gene

Rab5a - RAB5A, member RAS oncogene family Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 64633 | 基因类型: protein coding

关于 Rab5a

功能概要

Enables GDP-dissociation inhibitor binding activity. Involved in several processes, including positive regulation of smooth muscle cell migration; positive regulation of smooth muscle cell proliferation; and regulation of long-term neuronal synaptic plasticity. Located in several cellular components, including cytoplasmic vesicle; neuronal cell body; and perinuclear region of cytoplasm. Part of protein-containing complex. Is anchored component of synaptic vesicle membrane. Orthologous to human RAB5A (RAB5A, member Ras oncogene family). [provided by Alliance of Genome Resources, Apr 2022]

Rab5a 基因产物(1)

mRNA Protein Name
NM_022692.2 NP_073183.1 ras-related protein Rab-5A
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables GDP-dissociation inhibitor binding IDA
IDA: 通过直接分析推断
14709549 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in endocytosis IMP
IMP: 通过突变表型推断
16154939 RGD
involved in endosome organization IMP
IMP: 通过突变表型推断
8043272 RGD
involved in positive regulation of smooth muscle cell migration IMP
IMP: 通过突变表型推断
21125971 RGD
involved in positive regulation of smooth muscle cell proliferation IMP
IMP: 通过突变表型推断
21125971 RGD
involved in postsynaptic neurotransmitter receptor internalization IDA
IDA: 通过直接分析推断
15629704 RGD
involved in postsynaptic neurotransmitter receptor internalization IMP
IMP: 通过突变表型推断
15629704 RGD
involved in regulation of long-term neuronal synaptic plasticity IMP
IMP: 通过突变表型推断
18653660 RGD
involved in synaptic vesicle endocytosis IDA
IDA: 通过直接分析推断
20956291 RGD
involved in synaptic vesicle endocytosis IMP
IMP: 通过突变表型推断
20956291 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
8043272 RGD
located in axon terminus IDA
IDA: 通过直接分析推断
8043272 RGD
located in dendrite IDA
IDA: 通过直接分析推断
8043272 RGD
located in early endosome IDA
IDA: 通过直接分析推断
18353411 RGD
located in endosome IDA
IDA: 通过直接分析推断
8043272 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
15629704 RGD
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
15629704 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
8043272 RGD
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
12703553 RGD
is active in postsynaptic endocytic zone membrane IDA
IDA: 通过直接分析推断
15629704 RGD
is active in postsynaptic endocytic zone membrane IMP
IMP: 通过突变表型推断
15629704 RGD
is active in presynaptic endosome IDA
IDA: 通过直接分析推断
31074746 RGD
is active in presynaptic endosome IMP
IMP: 通过突变表型推断
31074746 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
14709549 RGD
located in recycling endosome IDA
IDA: 通过直接分析推断
10468577 RGD
located in somatodendritic compartment IDA
IDA: 通过直接分析推断
8043272 RGD
located in synaptic vesicle IDA
IDA: 通过直接分析推断
8043272 RGD
is active in synaptic vesicle membrane EXP
EXP: 通过实验结果推断
20926670 RGD
is active in synaptic vesicle membrane IDA
IDA: 通过直接分析推断
20926670 RGD
located in synaptic vesicle membrane IDA
IDA: 通过直接分析推断
20926670 RGD
is active in synaptic vesicle membrane IMP
IMP: 通过突变表型推断
20926670 RGD
located in zymogen granule membrane IDA
IDA: 通过直接分析推断
8166729 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ras-related protein Rab-5A

small GTP-binding protein rab5

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11571 RAB5A Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21715 Rab5a Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28233 Rab5a Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rab5a NCBI NCBI:5868
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