2. Gene
  3. Abhd6 - abhydrolase domain containing 6 Gene

Abhd6 - abhydrolase domain containing 6 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: 0610041D24Rik

基因 ID: 66082 | 基因类型: protein coding

关于 Abhd6

功能概要

Enables acylglycerol Lipase activity and Phospholipase activity. Involved in several processes, including monoacylglycerol catabolic process; negative regulation of cold-induced thermogenesis; and phospholipid metabolic process. Acts upstream of or within long-term synaptic depression; negative regulation of cell migration; and regulation of endocannabinoid signaling pathway. Located in late endosome membrane; lysosomal membrane; and mitochondrion. Is integral component of postsynaptic membrane. Part of AMPA glutamate receptor complex. Is active in GABA-ergic synapse and glutamatergic synapse. Orthologous to human ABHD6 (abhydrolase domain containing 6, acylglycerol Lipase). [provided by Alliance of Genome Resources, Apr 2022]

Abhd6 基因产物(3)

mRNA Protein Name
NM_001331064.1 NP_001317993.1 monoacylglycerol lipase ABHD6 isoform 1
NM_001331065.1 NP_001317994.1 monoacylglycerol lipase ABHD6 isoform 2
NM_025341.4 NP_079617.2 monoacylglycerol lipase ABHD6 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables monoacylglycerol lipase activity IDA
IDA: 通过直接分析推断
18096503 MGI
enables monoacylglycerol lipase activity IMP
IMP: 通过突变表型推断
20657592 MGI
enables phospholipase activity IDA
IDA: 通过直接分析推断
24095738 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in acylglycerol catabolic process IDA
IDA: 通过直接分析推断
18096503 MGI
acts upstream of or within long-term synaptic depression IMP
IMP: 通过突变表型推断
20657592 MGI
involved in lysobisphosphatidic acid metabolic process IDA
IDA: 通过直接分析推断
26491015 MGI
involved in monoacylglycerol catabolic process IDA
IDA: 通过直接分析推断
26491015 MGI
acts upstream of or within negative regulation of cell migration IMP
IMP: 通过突变表型推断
20657592 MGI
involved in negative regulation of cold-induced thermogenesis IMP
IMP: 通过突变表型推断
26997277 MGI
involved in phospholipid catabolic process IDA
IDA: 通过直接分析推断
24095738 MGI
involved in positive regulation of lipid biosynthetic process IMP
IMP: 通过突变表型推断
24095738 MGI
acts upstream of or within regulation of endocannabinoid signaling pathway IMP
IMP: 通过突变表型推断
20657592 MGI
involved in regulation of retrograde trans-synaptic signaling by endocanabinoid EXP
EXP: 通过实验结果推断
20657592 MGI
involved in regulation of retrograde trans-synaptic signaling by endocanabinoid IDA
IDA: 通过直接分析推断
20657592 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of AMPA glutamate receptor complex IDA
IDA: 通过直接分析推断
22632720 MGI
is active in GABA-ergic synapse IDA
IDA: 通过直接分析推断
20657592 MGI
is active in glutamatergic synapse EXP
EXP: 通过实验结果推断
20657592 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
20657592 MGI
located in late endosome membrane IDA
IDA: 通过直接分析推断
26491015 MGI
located in lysosomal membrane IDA
IDA: 通过直接分析推断
26491015 MGI
located in membrane IDA
IDA: 通过直接分析推断
18096503 MGI
located in mitochondrion IDA
IDA: 通过直接分析推断
20657592 MGI
is active in postsynaptic membrane IDA
IDA: 通过直接分析推断
20657592 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

monoacylglycerol lipase ABHD6

2-arachidonoylglycerol hydrolase

相关产品

Pre-clinical Phase
生物活性分子 (29)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-136924 FP-Biotin 95.15% 否
HY-110148 WWL113 Inhibitor 99.72% 否
HY-100337 WWL70 Inhibitor 99.95% 否
HY-120177 KT182 Inhibitor 99.77% 否
HY-120215 KT203 Inhibitor 99.86% 否
HY-101457 JZP-430 Inhibitor 99.74% 否
HY-125143 ABC34 Inhibitor 99.90% 否
HY-152148 JZP-MA-11 Inhibitor 99.26% 否
HY-114926 KT185 Inhibitor 99.37% 否
HY-121422 JZP-361 Inhibitor 99.63% 否
HY-132310 MAGL-IN-4 Inhibitor 99.79% 否
HY-124314 LEI-106 Inhibitor 99.9% 否
HY-18544 AA38-3 Inhibitor 99.95% 否
HY-132246 WWL123 analogue-1 Inhibitor 98.04% 否
HY-103463 SA57 Inhibitor ≥99.0% 否
HY-110178 WWL123 Inhibitor 98.0% 否
HY-116212 JCP-170 Inhibitor / 否
HY-116793 Dimepiperate / 否
HY-117722 JW 618 Inhibitor / 否
HY-120126 ML378 Inhibitor / 否
HY-120171 DH-376 Inhibitor / 否
HY-126031 (R)-KT109 Inhibitor / 否
HY-152152 JZP-MA-13 Inhibitor / 否
HY-158338 ABHD antagonist 1 Antagonist / 否
HY-158339 ABHD antagonist 2 Antagonist / 否
HY-RS00097 ABHD6 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-126031A (S)-KT109 / 否
HY-RS16727 Abhd6 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23163 Abhd6 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Abhd6 NCBI NCBI:57406
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