1. Gene
  2. Jarid2 - jumonji and AT-rich interaction domain containing 2 Gene

Jarid2 - jumonji and AT-rich interaction domain containing 2 Gene

种属: Rattus norvegicus

基因 ID: 681740 | 基因类型: protein coding

关于 Jarid2

功能概要

Predicted to enable several functions, including Histone Demethylase activity; ubiquitin binding activity; and ubiquitin modification-dependent histone binding activity. Involved in negative regulation of cardiac muscle cell proliferation and negative regulation of cardiac muscle hypertrophy. Predicted to be located in mitochondrion and nucleoplasm. Predicted to be part of ESC/E(Z) complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human JARID2 (jumonji and AT-rich interaction domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]

Jarid2 基因产物(8)

mRNA Protein Name
XM_039096474.1 XP_038952402.1 protein Jumonji isoform X3
XM_017600709.2 XP_017456198.1 protein Jumonji isoform X3
XM_017600710.2 XP_017456199.1 protein Jumonji isoform X3
XM_017600708.2 XP_017456197.1 protein Jumonji isoform X3
XM_039096473.1 XP_038952401.1 protein Jumonji isoform X3
XM_039096472.1 XP_038952400.1 protein Jumonji isoform X2
XM_017600711.2 XP_017456200.1 protein Jumonji isoform X4
XM_017600707.2 XP_017456196.1 protein Jumonji isoform X1
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of cardiac muscle cell proliferation IDA
IDA: 通过直接分析推断
26298346 RGD
involved in negative regulation of cardiac muscle cell proliferation IMP
IMP: 通过突变表型推断
26298346 RGD
involved in negative regulation of cardiac muscle hypertrophy IGI
IGI: 通过遗传相互作用推断
24657879 RGD
involved in negative regulation of cardiac muscle hypertrophy IMP
IMP: 通过突变表型推断
24657879 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

protein Jumonji

jumonji, AT rich interactive domain 2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Jarid2 NCBI NCBI:3720